Document Detail

Increased levels of mean platelet volume: a possible relationship with idiopathic sudden hearing loss.
MedLine Citation:
PMID:  23341093     Owner:  NLM     Status:  MEDLINE    
Mean platelet volume (MPV) is one of the platelet function indices which reflects the platelet production rate and functions. While vascular occlusion, acute or chronic syndromes and vasculitis are increasing the MPV levels, infections, autoimmune diseases, and inflammatory situations reduce it. The indicator for idiopathic sudden sensorineural hearing loss (ISHL) etiology remains a matter of debate because it is associated with many different disorders. We evaluated MPV levels in ISHL patients. Forty patients with ISHL and 40 healthy, age and sex matched subjects were enrolled to the study. Audiometer and laboratory results were recorded. Comparative multivariate analyses between indicator factors and hearing outcomes were conducted. MPV and platelet distribution width is significantly higher in ISHL. Platelet count is lower in the ISHL than control group (p < 0.001), (p < 0.001), (p = 0.003), respectively. Our findings indicate that, ISHL appears to be characterized by ischaemic or thrombotic events. Considering the increased MPV levels; MPV may be used to evaluate ISHL as an hepler indicator.
Sahin Ulu; M Sena Ulu; Ahmet Ahsen; Fatih Yucedag; Abdullah Aycicek; Sefa Celik
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Publication Detail:
Type:  Journal Article     Date:  2013-01-23
Journal Detail:
Title:  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery     Volume:  270     ISSN:  1434-4726     ISO Abbreviation:  Eur Arch Otorhinolaryngol     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-10-07     Completed Date:  2014-05-26     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  9002937     Medline TA:  Eur Arch Otorhinolaryngol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  2875-8     Citation Subset:  IM    
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MeSH Terms
Case-Control Studies
Hearing Loss, Sudden / blood*
Mean Platelet Volume*
Middle Aged
Multivariate Analysis
Platelet Count
Comment In:
Eur Arch Otorhinolaryngol. 2014 Sep;271(9):2595-6   [PMID:  24639340 ]

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