| Increased intraventricular velocities: an unrecognized cause of systolic murmur in adults. | |
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MedLine Citation:
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PMID: 9822083 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: The purpose of this study was to determine the frequency, clinical features and echocardiographic characteristics of increased intraventricular velocities (IIVs) in patients referred to the echocardiography laboratory for systolic murmur. BACKGROUND: A subset of patients referred to the echocardiography laboratory for evaluation of a systolic murmur have IIVs in the absence of other recognized causes of systolic murmur. METHODS: We prospectively studied echocardiograms from 108 consecutive patients referred for evaluation of a systolic murmur. Clinical data were obtained from patient examinations and medical records. RESULTS: The sole explanation for systolic murmur was IIVs in 16.7% of referred patients. Compared with those without IIVs, patients with IIVs had a higher ejection fraction (EF) (58.7+/-7.8% vs. 51.1+/-12.5%, p < 0.001), percent fractional shortening (42.3+/-9.7% vs. 31.0+/-11.4%, p < 0.0001), left ventricular (LV) mass index (181+/-70 vs. 152+/-48 g/m2, p=0.046) and prevalence of hypertension (73.3% vs. 51.7%, p=0.043) and a lower prevalence of segmental wall motion abnormalities (2.2% vs. 39.3%, p < 0.001). CONCLUSIONS: Increased intraventricular velocities are a common cause of systolic murmur in this group of patients and should be included in the differential diagnosis of systolic murmurs in adults. The association of IIVs with LV hypertrophy should be a clinical consideration when these murmurs are identified. |
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Authors:
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P H Spooner; M P Perry; R O Brandenburg; G D Pennock |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the American College of Cardiology Volume: 32 ISSN: 0735-1097 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 1998 Nov |
Date Detail:
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Created Date: 1998-12-16 Completed Date: 1998-12-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1589-95 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Tucson Veterans Affairs Medical Center and University of Arizona 85723, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Auscultation Blood Flow Velocity / physiology* Coronary Circulation / physiology* Echocardiography Echocardiography, Doppler Female Heart Murmurs / diagnosis, etiology*, ultrasonography Humans Male Prospective Studies Systole Ventricular Function / physiology* |
| Comments/Corrections | |
Comment In:
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J Am Coll Cardiol. 1998 Nov 15;32(6):1596-602
[PMID:
9822084
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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