| Increased intra-abdominal pressure and cardiac filling pressures in obesity-associated pseudotumor cerebri. | |
| | |
MedLine Citation:
|
PMID: 9270586 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: To determine whether intra-abdominal pressure (as estimated from urinary bladder pressure) is elevated in patients with central obesity (as measured by sagittal abdominal diameter) and pseudotumor cerebri and whether this increased intra-abdominal pressure is associated with increased pleural pressure and cardiac filling pressure, implying a resistance to venous return from the brain. DESIGN: Nonrandomized, prospective. SETTING: University hospital, operating room. MAIN OUTCOME MEASUREMENTS: Intracranial pressure, urinary bladder pressure, sagittal abdominal diameter, transesophageal pleural pressure, central venous pressure, pulmonary artery pressure, and pulmonary artery occlusion pressure. SUBJECTS: Six women with pseudotumor cerebri (one with CSF leak, one with lumboperitoneal shunt). RESULTS: Urinary bladder pressure (22 +/- 3 cm H2O) and sagittal abdominal diameter (29 +/- 3 cm) were significantly elevated in these patients with elevated intracranial pressure (293 +/- 80 mm H2O) compared with a previously reported group of nonobese control patients. The transesophageal pleural pressure (15 +/- 10 mm Hg), central venous pressure (20 +/- 6 mm Hg), mean pulmonary artery pressure (31 +/- 6 mm Hg), and pulmonary artery occlusion pressure (21 +/- 7 mm Hg) were all markedly elevated compared with published normal values and with previous data from obese patients without pseudotumor cerebri. CONCLUSIONS: These data support the hypothesis that central obesity raises intra-abdominal pressure, which increases pleural pressure and cardiac filling pressure, which impede venous return from the brain, leading to increased intracranial venous pressure and increased intracranial pressure associated with pseudotumor cerebri. |
| | |
Authors:
|
H J Sugerman; E J DeMaria; W L Felton; M Nakatsuka; A Sismanis |
Related Documents
:
|
3602916 - A pitfall in the measurement of arterial blood pressure in the ischaemic limb during el... 12046036 - Correction of discrepancy between prescribed and actual blood flow rates in chronic hem... 36596 - Effect of variations in blood hydrogen ion concentration on pulmonary gas exchange of a... 1120756 - Pulmonary venous waterfall and perivenous pressure in the living dog. 18174766 - Nocturnal blood pressure elevation predicts progression of albuminuria in elderly peopl... 10758046 - Correction of arterial structure and endothelial dysfunction in human essential hyperte... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Neurology Volume: 49 ISSN: 0028-3878 ISO Abbreviation: Neurology Publication Date: 1997 Aug |
Date Detail:
|
Created Date: 1997-09-17 Completed Date: 1997-09-17 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0401060 Medline TA: Neurology Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 507-11 Citation Subset: AIM; IM |
Affiliation:
|
Department of Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abdomen
/
physiopathology* Adult Coronary Circulation* Female Gastric Bypass Headache / etiology Heart / physiopathology* Humans Obesity / complications*, surgery Pressure Prospective Studies Pseudotumor Cerebri / etiology*, physiopathology* Tinnitus / etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Frequent and frequently overlooked: treatment-induced endocrine dysfunction in adult long-term survi...
Next Document: Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease.