Document Detail

Increased intestinal absorption by segmental reversal of the small bowel in adult patients with short-bowel syndrome: a case-control study.
MedLine Citation:
PMID:  23151533     Owner:  NLM     Status:  Publisher    
BACKGROUND: Segmental reversal of the small bowel (SRSB) is proposed in patients with short-bowel syndrome (SBS) as a rehabilitative therapy, but its effects on absorption have not been studied. OBJECTIVE: We aimed to determine intestinal macronutrient absorption and home parenteral nutrition (HPN) dependence in SBS patients with intestinal failure. DESIGN: We included in a retrospective study all consecutive patients who had an SRSB between 1985 and 2010 and underwent a study of macronutrient absorption. Patients were matched to SBS controls with the same digestive characteristics. Energy and macronutrient absorption were measured. The dependence on HPN was expressed by the number of infusions per week and by the calories infused daily divided by the basal energy expenditure multiplied by 1.5. RESULTS: Seventeen patients who had an SRSB were matched to 17 control patients. Intestinal absorption was higher in the SRSB group for total calories (69.5% compared with 58.0%), fat (48.4% compared with 33.2%), and protein (62.7% compared with 53.4%) (P < 0.05). Median oral autonomy was 100% ± 38.4% in the SRSB group, whereas it was 79% ± 39.6% in the control group (P < 0.05). The number of calories infused was lower in the SRSB group (500 ± 283 compared with 684 ± 541; P < 0.05), as was HPN dependence (33% ± 20% compared with 48% ± 38%; P < 0.05) at the time of the study. CONCLUSION: SRSB allows a gain in macronutrient absorption, which is associated with a lower HPN dependence. To our view, SRSB should be integrated in intestinal rehabilitative adult programs.
Sabrina Layec; Laura Beyer; Olivier Corcos; Arnaud Alves; Xavier Dray; Aurélien Amiot; Carmen Stefanescu; Benoit Coffin; Frédéric Bretagnol; Yoram Bouhnik; Bernard Messing; Yves Panis; Nathalie Kapel; Francisca Joly
Related Documents :
15374843 - Associated loss of fat-free mass and bone mineral density in chronic obstructive pulmon...
17639593 - Analysis of 88 adult patients referred for genetics evaluation.
12816353 - Operating data and unsolved problems of the dicom modality worklist: an indispensable t...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-14
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  -     ISSN:  1938-3207     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Departments of Gastroenterology and Nutrition Support and Colorectal Surgery, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris and the Denis Diderot University, Paris, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effects of vitamin A and ?-carotene supplementation on birth size and length of gestation in rural B...
Next Document:  Fetal growth, omega-3 (n-3) fatty acids, and progression of subclinical atherosclerosis: preventing ...