Document Detail


Increased incidence of stroke and impaired prognosis after stroke among patients with seropositive rheumatoid arthritis.
MedLine Citation:
PMID:  19772797     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To examine the incidence of, and outcome after, a stroke in patients with rheumatoid arthritis (RA) compared with the general population. METHODS: The northern Sweden MONICA register was used to compare the incidence of stroke in a cohort of RA patients with the general population. Forty RA patients who had also suffered a stroke were identified. For each patient with RA, three controls with a history of stroke but without RA were randomly collected from the same register, and matched for age and sex. RESULTS: The standardised incidence ratio (SIR) for stroke was 2.7 in RA patients compared with the general population (p<0.05). During the follow-up, RA patients had a higher overall case fatality (CF) following stroke compared with controls (hazard ratio (HR) =1.70, p<0.05). CONCLUSIONS: Both the incidence of a stroke, and the subsequent CF, were higher among RA patients compared with the general population. The results emphasize the necessity of optimising the prevention of stroke and follow-up care after a stroke in RA.
Authors:
A Södergren; B Stegmayr; M-L Ohman; S Wållberg-Jonsson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical and experimental rheumatology     Volume:  27     ISSN:  0392-856X     ISO Abbreviation:  Clin. Exp. Rheumatol.     Publication Date:    2009 Jul-Aug
Date Detail:
Created Date:  2009-09-23     Completed Date:  2009-11-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308521     Medline TA:  Clin Exp Rheumatol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  641-4     Citation Subset:  IM    
Affiliation:
Department of Public Health and Clinical Medicine, Rheumatology, University of Umeå, Umeå, Sweden. anna.sodergren@medicin.umu.se
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MeSH Terms
Descriptor/Qualifier:
Aged
Arthritis, Rheumatoid / epidemiology*,  mortality,  pathology
Cohort Studies
Comorbidity
Female
Humans
Incidence
Male
Prognosis
Stroke / epidemiology*,  mortality,  pathology
Survival Rate
Sweden / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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