Document Detail

Increased gingival blood vessel density in SLE patients.
MedLine Citation:
PMID:  22532958     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Systemic lupus erythematosus (SLE) is a serious multisystem disease with a variety of cutaneous and oral manifestations. It is an autoimmune disorder whereby patients develop autoantibodies to many of their cells, cell components, and tissue. The microvascular changes in SLE play a role in the pathogenesis of this disease. The aim of this study was to investigate the gingival microcirculation in SLE patients.
METHOD AND MATERIALS: Fifteen SLE patients and 15 healthy subjects were recruited for this study. Gingival microcirculation was investigated using videocapillaroscopy, a noninvasive technique that permits the in vivo evaluation of microvascular patterns.
RESULTS: Significant differences between patients and controls for the capillary density were seen. An increase of mean capillary density was observed in SLE patients (105.5 ± 3.41) (P < .05).
CONCLUSION: This study showed significant modifications of gingival microcirculation in SLE patients.
Giuseppe Alessandro Scardina; Pietro Messina
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Quintessence international (Berlin, Germany : 1985)     Volume:  43     ISSN:  1936-7163     ISO Abbreviation:  Quintessence Int     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-04-25     Completed Date:  2012-10-24     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  0342677     Medline TA:  Quintessence Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  511-5     Citation Subset:  D    
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MeSH Terms
Capillaries / pathology*
Dental Plaque Index
Gingiva / blood supply*
Lupus Erythematosus, Systemic / pathology*
Microscopic Angioscopy
Middle Aged
Periodontal Index

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