Document Detail


Increased frequencies of hysterectomy and early menopause in fibromyalgia patients: a comparative study.
MedLine Citation:
PMID:  19169621     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective was to determine the relationship between symptoms of fibromyalgia (FM) and early menopause and hysterectomy. We included 115 postmenopausal patients with FM (mean age 54.6 +/- 7.6) and 67 rheumatoid arthritis (RA) patients (mean age 55.5 +/- 9) into our study. All patients were questioned about the severity of their symptoms of FM, anxiety, and depression by using a visual analog scale and FM impact questionnaire. Patients' history of menopause and hysterectomy were recorded. Menopause (<or=45 years) was accepted to be early. The frequencies of early menopause (38.3% vs. 13.4%, p = 0.001) and hysterectomy (16.5% vs. 6%, p = 0.039) in FM patients were significantly higher than in RA patients. While chronic widespread pain and other FM-related symptoms started after menopause in 58.3% of FM patients, the disease started after menopause in 64.2% of RA patients (p > 0.05). FM-related symptoms started in 30 patients (26.1%) with FM with menopause or within the first postmenopausal year. When the clinical features of FM patients whose symptoms started within the first menopausal year were compared to other FM patients; it was observed that the frequency of early menopause was higher in the former group (p = 0.048). Duke anxiety and depression score was higher in patients with hysterectomy whose FM symptoms started within the first year of post-hysterectomy than other FM patients (9.1 +/- 2.7 vs. 6.7 +/- 2.7, p = 0.022). Early menopause and hysterectomy may be one of the factors contributing to the development of FM.
Authors:
Omer Nuri Pamuk; Salim Dönmez; Necati Cakir
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-01-24
Journal Detail:
Title:  Clinical rheumatology     Volume:  28     ISSN:  1434-9949     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-03     Completed Date:  2009-08-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  561-4     Citation Subset:  IM    
Affiliation:
Department of Rheumatology, Trakya University Medical Faculty, Edirne, Turkey. omernpamuk@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Arthritis, Rheumatoid / complications*,  therapy
Depression
Female
Fibromyalgia / complications*,  epidemiology,  etiology*
Humans
Hysterectomy / statistics & numerical data*
Menopause, Premature*
Middle Aged
Postmenopause
Questionnaires
Research Design
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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