Document Detail


Increased fluid intake does not augment capacity to lay down new collagen in nursing home residents at risk for pressure ulcers: a randomized, controlled clinical trial.
MedLine Citation:
PMID:  19821962     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Prevention of pressure ulcers is fundamental to safe care of nursing home residents yet the role of hydration in pressure ulcer prevention has not been systematically examined. This randomized clinical trial was undertaken to determine whether administration of supplemental fluid to nursing home residents at risk for pressure ulcers would enhance collagen deposition, increase estimated total body water, augment subcutaneous tissue oxygenation, and was safe. After a baseline period, 64 subjects were randomized to receive the fluid volume prescribed or additional fluid (prescribed plus 10 mL/kg) for 5 days. Participants' potential to heal as measured with hydroxyproline was low at baseline and did not increase significantly during treatment when additional fluid was systematically provided. Fluid intake increased significantly during treatment. Estimates of total body water and subcutaneous oxygen did not increase, indicating hydration was not improved. Supplemental fluid did not result in overhydration as measured by clinical parameters. Further work is needed to examine the relationship between fluid intake and hydration in nursing home residents as well as the role of hydration in pressure ulcer prevention.
Authors:
Nancy A Stotts; Harriet W Hopf; Jeanie Kayser-Jones; Glenn M Chertow; Bruce A Cooper; Horng-Shiuann Wu
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2009-10-12
Journal Detail:
Title:  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society     Volume:  17     ISSN:  1524-475X     ISO Abbreviation:  Wound Repair Regen     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-11-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9310939     Medline TA:  Wound Repair Regen     Country:  United States    
Other Details:
Languages:  eng     Pagination:  780-8     Citation Subset:  IM    
Affiliation:
Department of Physiological Nursing, University of California San Francisco, San Francisco, California, USA. nancy.stotts@nursing.ucsf.edu
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R01 NR008241/NR/NINR NIH HHS

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