Document Detail


Increased fetal iron load in rhesus hemolytic disease.
MedLine Citation:
PMID:  15205095     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is little information about the iron overload caused by hemolysis in fetuses affected with rhesus hemolytic disease (RHD). The authors therefore studied the iron load in RHD by measuring cord blood ferritin levels in babies affected with RHD and gestational age- and weight-matched controls. Cord blood ferritin levels were higher in babies with RHD. Intrauterine transfusions did not affect the ferritin status of the babies with RHD and there was no correlation between hemoglobin and ferritin levels. The results indicate that there is an increased intrauterine iron load in babies with RHD, independent from intrauterine transfusions and rate of hemolysis.
Authors:
Canan Aygun; Gülsevin Tekinalp; Aytemiz Gurgey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric hematology and oncology     Volume:  21     ISSN:  0888-0018     ISO Abbreviation:  Pediatr Hematol Oncol     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-06-18     Completed Date:  2005-03-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8700164     Medline TA:  Pediatr Hematol Oncol     Country:  England    
Other Details:
Languages:  eng     Pagination:  329-33     Citation Subset:  IM    
Affiliation:
Hacettepe University Faculty of Medicine, Department of Pediatrics, Neonatology Unit, Ankara, Turkey. cananaygun2@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Case-Control Studies
Erythroblastosis, Fetal / complications*,  diagnosis,  epidemiology
Female
Ferritins / blood
Fetal Blood / chemistry
Humans
Infant, Newborn
Iron Overload / epidemiology,  etiology*
Male
Pregnancy
Prenatal Diagnosis
Rh-Hr Blood-Group System*
Turkey / epidemiology
Chemical
Reg. No./Substance:
0/Rh-Hr Blood-Group System; 9007-73-2/Ferritins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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