| Increased erythropoietin production in children with severe malarial anemia. | |
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MedLine Citation:
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PMID: 7485716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Plasma immunoreactive erythropoietin concentrations were determined in 84 children with Plasmodium falciparum malaria in Gabon. There was an inverse log/linear relationship between hemoglobin or hematocrit and plasma erythropoietin, indicating that erythropoietin levels increased exponentially as circulating hemoglobin decreased. These result show that P. falciparum malaria does not lead to decreased erythropoietin production, and in turn reduced erythropoietin production does not contribute to the pathogenesis of malarial anemia. There is an adequate response of erythropoietin to anemia in children with P. falciparum malaria. |
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Authors:
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G D Burchard; P Radloff; J Philipps; M Nkeyi; J Knobloch; P G Kremsner |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 53 ISSN: 0002-9637 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 1995 Nov |
Date Detail:
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Created Date: 1995-12-28 Completed Date: 1995-12-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 547-51 Citation Subset: AIM; IM |
Affiliation:
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Institute for Tropical Medicine, University of Tubingen, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Anemia / etiology, metabolism*, therapy Blood Transfusion Child Child, Preschool Erythropoietin / biosynthesis* Female Hematocrit Hemoglobins / analysis Humans Infant Malaria, Falciparum / complications* Male Parasitemia / complications* Regression Analysis Severity of Illness Index |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins; 11096-26-7/Erythropoietin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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