Document Detail


Increased contralateral cerebellar uptake of technetium-99m-HMPAO on ictal brain SPECT.
MedLine Citation:
PMID:  8772637     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Crossed cerebellar diaschisis (CCD) is a well-known brain SPECT finding in stroke patients. Two reports, however, have described supratentorial and contralateral cerebellar hyperperfusion (crossed cerebellar hyperperfusion) on ictal brain SPECT in epileptic patients. The purpose of this study was to assess the usefulness of crossed cerebellar hyperperfusion (CCH) for the detection of epileptic foci on ictal scan. METHODS: Twelve patients with complex partial seizures having characteristic clinical, electroencephalographic (EEG) and brain SPECT findings were included. Fifteen to 20 mCi 99mTc-HMPAO were injected intravenously during the seizure period or the aura for the ictal SPECT study. The SPECT findings were visually assessed to determine whether the finding of CCH was valuable in the localization of ictal foci. RESULTS: Epileptic foci were found in the right temporal (n = 6), left temporal (n = 4), right occipital (n = 1) and left frontal (n = 1) areas. CCH was observed in 8 (75%) of the 12 patients. In two patients, contralateral cerebellar uptake was more obvious than that in the epileptic foci. In the interictal scans, cerebellar activity, which was increased in ictal period, was equalized in seven of eight patients, while perfusion was diminished in the remaining patient. CONCLUSION: CCH is a frequent finding of ictal brain SPECT and may aid in the lateralization of epileptic foci.
Authors:
J H Won; J D Lee; T S Chung; C Y Park; B I Lee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of nuclear medicine : official publication, Society of Nuclear Medicine     Volume:  37     ISSN:  0161-5505     ISO Abbreviation:  J. Nucl. Med.     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1997-01-06     Completed Date:  1997-01-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0217410     Medline TA:  J Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  426-9     Citation Subset:  IM    
Affiliation:
Department of Radiology and Neurology, Yonsei University College of Medicine, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Brain / radionuclide imaging
Cerebellum / blood supply,  radionuclide imaging*
Cerebrovascular Circulation / physiology*
Child
Child, Preschool
Electroencephalography
Epilepsy, Complex Partial / physiopathology,  radionuclide imaging*
Female
Humans
Incidence
Male
Organotechnetium Compounds / diagnostic use*
Oximes / diagnostic use*
Technetium Tc 99m Exametazime
Chemical
Reg. No./Substance:
0/Organotechnetium Compounds; 0/Oximes; 100504-35-6/Technetium Tc 99m Exametazime

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