Document Detail

Increased comorbidities in heart failure patients ≥85years but declined from >90years: Data from the Swedish Heart Failure Registry.
MedLine Citation:
PMID:  22805544     Owner:  NLM     Status:  Publisher    
OBJECTIVES: Epidemiological studies of elderly heart failure (HF) patients (≥85years) are limited with inconsistent findings. Our objective is to confirm and extend epidemiological study in elderly (≥85years) patients using the Swedish Heart Failure Registry database. METHODS: This retrospective study included 8,347 HF patients aged ≤65years and 15,889 HF patients aged ≥85years. Elderly population was further divided into two subgroups: 11,412 patients were 85-90years and 4,477 patients were >90years. RESULTS: The ≥85year group was characterized by more women, higher systolic blood pressure (SBP), lower body-mass index (BMI), more than twice as many HF with normal left ventricular ejection fraction (HFNEF), higher incidence of cardiovascular and non-cardiovascular comorbidities and less use of proven therapeutics compared with the ≤65year group. Compared with the 85-90year subgroup, the >90year subgroup had a decline in cardiovascular and non-cardiovascular comorbidities except renal insufficiency and anaemia which continued to increase with ageing (p<0.01). Tendency was the same regardless of gender but slightly different between systolic HF (SHF) and HFNEF. In the group with HFNEF, there were more women, higher SBP, lower N-terminal pro-B-type natriuretic peptide levels, less ischaemic heart disease, more hypertension and left bundle branch block regardless of age. Atrial fibrillation was more frequent in patients with HFNEF than with SHF in the elderly group (p<0.01). Patients with HFNEF in the >90year subgroup had increasing incidence of ischaemic heart disease compared to 85-90year group (p<0.01). CONCLUSIONS: HF patients ≥85years had increased cardiovascular and non-cardiovascular comorbidities but with a decline from >90years.
Alexandra Holmström; Runa Sigurjonsdottir; Magnus Edner; Asa Jonsson; Ulf Dahlström; Michael Lx Fu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-15
Journal Detail:
Title:  International journal of cardiology     Volume:  -     ISSN:  1874-1754     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Crown Copyright © 2012. Published by Elsevier Ireland Ltd. All rights reserved.
Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.
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