Document Detail

Increased bone marrow blood flow in rabbits with acute hemolytic anemia.
MedLine Citation:
PMID:  3953565     Owner:  NLM     Status:  MEDLINE    
The bone marrow blood flow in the femur of the rabbit with acute hemolytic anemia was measured by the radioactive microsphere method. Acute hemolytic anemia was induced by a single intraperitoneal injection of phenylhydrazine. An increase in the bone marrow blood flow was detected three days after the induction of anemia and continued for about one week. The bone marrow blood flow of the anemic rabbit (66 ml/min/100 g marrow) was about three times that of the control (20 ml/min/100 g marrow). The increased blood flow to the bone marrow appeared to be correlated to the increased erythropoietic activity.
L T Chen; M F Chen; V L Porter
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of hematology     Volume:  22     ISSN:  0361-8609     ISO Abbreviation:  Am. J. Hematol.     Publication Date:  1986 May 
Date Detail:
Created Date:  1986-04-18     Completed Date:  1986-04-18     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7610369     Medline TA:  Am J Hematol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  35-41     Citation Subset:  IM    
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MeSH Terms
Acute Disease
Anemia, Hemolytic / blood*
Bone Marrow / blood supply*
Cardiac Output
Femur / blood supply,  drug effects
Phenylhydrazines / pharmacology
Regional Blood Flow
Grant Support
Reg. No./Substance:
0/Phenylhydrazines; 100-63-0/phenylhydrazine

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