Document Detail


Increased blood pressure reactions to acute mental stress are associated with 16-year cardiovascular disease mortality.
MedLine Citation:
PMID:  22958235     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Exaggerated cardiovascular reactions to acute psychological stress may be involved in the etiology of cardiovascular pathology. The present analysis examined the association between the magnitude of systolic and diastolic blood pressure reactions to stress and cardiovascular disease mortality. Participants were 431 (229 women) from the West of Scotland Twenty-07 Study, aged 63 years at the time of stress testing, where blood pressure was measured during resting baseline and mental arithmetic stress. Participants' vital status was tracked for the next 16 years, during which time 38 had died of cardiovascular disease. Both systolic and diastolic blood pressure reactions were positively associated with cardiovascular disease mortality. This association could reflect the long-term erosive effects of exaggerated reactivity on the vasculature as well as its short-term capacity to trigger acute cardiovascular events.
Authors:
Douglas Carroll; Annie T Ginty; Geoff Der; Kate Hunt; Michaela Benzeval; Anna C Phillips
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-09-07
Journal Detail:
Title:  Psychophysiology     Volume:  49     ISSN:  1540-5958     ISO Abbreviation:  Psychophysiology     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-18     Completed Date:  2013-02-12     Revised Date:  2014-10-14    
Medline Journal Info:
Nlm Unique ID:  0142657     Medline TA:  Psychophysiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1444-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Society for Psychophysiological Research.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Aged
Aged, 80 and over
Blood Pressure / physiology*
Cardiovascular Diseases / mortality*,  physiopathology*
Cohort Studies
Data Interpretation, Statistical
Female
Humans
Male
Middle Aged
Stress, Psychological / physiopathology*,  psychology
Survival Analysis
Grant Support
ID/Acronym/Agency:
53462//Medical Research Council; MC_U130059811//Medical Research Council; MC_U130059823//Medical Research Council; MC_UP_A540_1021//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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