Document Detail


Increased blood [TAME]-esterase activity during exercise-induced asthma.
MedLine Citation:
PMID:  8032288     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twelve non-atopic asthmatic children who were reported to be suffering from exercise-induced asthma (E-IA), and eight non-asthmatic children, were studied in an attempt to discern possible associations between N-alpha-tosyl-L-arginine methyl ester [TAME]-esterase activity and E-IA, and the late asthmatic responses. Lung function tests and clinical examinations were performed at rest, and immediately and four hours after cycling for 6 min. Concomitant blood investigations revealed a consistent elevation in the asthmatics of [TAME]-esterase activity and peripheral blood eosinophil levels, immediately following exercise. Our findings suggest that E-IA is associated with a certain threshold of [TAME]-esterase activity as measured by a simple and a rapid colorimetric method.
Authors:
A H Subratty; N Kok-Shun
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of biomedical science     Volume:  50     ISSN:  0967-4845     ISO Abbreviation:  Br. J. Biomed. Sci.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1994-08-15     Completed Date:  1994-08-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9309208     Medline TA:  Br J Biomed Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  13-6     Citation Subset:  IM    
Affiliation:
SSR Centre for Medical Studies and Research, School of Science, University of Mauritius, Moka.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Asthma, Exercise-Induced / enzymology*
Child
Female
Humans
Male
Peptide Hydrolases / blood*
Chemical
Reg. No./Substance:
EC 3.4.-/Peptide Hydrolases; EC 3.4.-/tosylarginine methyl ester hydrolase

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