Document Detail

Increased arterial stiffness in children with a parental history of hypertension.
MedLine Citation:
PMID:  10089245     Owner:  NLM     Status:  MEDLINE    
The vascular dynamics of children with a parental history of hypertension has not been defined. The purpose of the current study was to determine whether or not these children have different arterial stiffness compared to the offspring of normotensive parents. One hundred healthy, nonobese subjects (ages 10-21 years) were divided into two groups of 50. Group A included the offspring of hypertensive patients and group B the offspring of normotensive parents. The variables studied were body surface area, blood pressure, and systolic and diastolic diameters of the aortic and carotid arteries as well as maximum velocity flow of these vessels. Carotid and aortic stiffness were calculated. Children and adolescents with a parental history of hypertension had higher carotid stiffness and smaller carotid diameters. These differences continued to be significant when correcting for body surface area. A higher blood pressure and a greater body surface area were also found.
E Meaney; V Samaniego; F Alva; R A Valdovinos; R Marrufo; A Vela; T Allen; A Misra; R Madsen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  20     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:    1999 May-Jun
Date Detail:
Created Date:  1999-04-20     Completed Date:  1999-04-20     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  203-5     Citation Subset:  IM    
Cardiovascular Unit, Regional Hospital "1 o de Octubre" ISSSTE, Mexico City, Mexico.
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MeSH Terms
Aorta / physiopathology,  ultrasonography*
Blood Flow Velocity
Blood Pressure
Carotid Artery, Common / physiopathology,  ultrasonography*
Hypertension / genetics,  physiopathology*,  ultrasonography
Myocardial Contraction
Nuclear Family
Ultrasonography, Doppler, Pulsed
Vascular Resistance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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