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Increased Maillard reaction products intake reduces phosphorus digestibility in male adolescent mice.
MedLine Citation:
PMID:  20122814     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To examine the effects of consuming diets rich in Maillard reaction products (MRPs) on phosphorus bioavailability in male adolescents.
METHODS: A 2-wk randomized two-period crossover trial was performed among healthy male adolescents aged 11-14 y (n = 20), with a 40-d washout period. The diets consumed were rich (brown diet) or poor (white diet) in MRPs. Three-day balances were performed on the last of each dietary period, and fasting blood samples were obtained. Dietary phosphorus utilization was examined by phosphorus intake in diet and phosphorus output in feces and urine, as measured colorimetrically by the vanadomolibdate procedure. Serum phosphorus, parathyroid hormone, and total alkaline phosphatase were determined.
RESULTS: A tendency to increase daily phosphorus fecal excretion was observed subsequent to the brown diet consumption compared with the white diet (P = 0.10), which led to significant reductions in phosphorus apparent absorption (P = 0.03) and fractional absorption (P = 0.04). Values of apparent phosphorus retention and bioavailability tended to decrease after the high-MRP diet. Serum parameters analyzed remained unchanged between diets and were within normal values.
CONCLUSION: The consumption of a rich-MRP diet in male adolescents had a negative influence on dietary phosphorus absorption, tending to decrease the phosphorus balance. Given the actual dietary habits of adolescents, possible long-term repercussions of this kind of diet should be studied.
Authors:
Cristina Delgado-Andrade; Isabel Seiquer; Marta Mesías García; Gabriel Galdó; M Pilar Navarro
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-02-01
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  27     ISSN:  1873-1244     ISO Abbreviation:  Nutrition     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  United States    
Other Details:
Languages:  eng     Pagination:  86-91     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Unit of Nutrition, Estación Experimental del Zaidín, High Spanish Council for Scientific Research, Granada, Spain. cdelgado@eez.csic.es
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