Document Detail


Increased Femoral Cartilage Thickness in Patients With Klinefelter Syndrome.
MedLine Citation:
PMID:  22954555     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The objective of this study was to determine femoral cartilage thickness (FCT) in patients with Klinefelter syndrome (KS), which is the most common sex chromosome disorder in men with varying degrees of androgen deficiency. This cross-sectional controlled study was conducted in a tertiary care center. Participants were 33 male patients (mean age = 36.2 years) with KS and 35 aged-matched healthy male controls (mean age = 32.9 years). Femoral condyle cartilage was measured by ultrasonography at three locations in each knee. Total testosterone, estradiol, sex hormone binding globulin, free androgen index, bioavailable testosterone, and albumin levels were measured. Femoral cartilage of patients at right and left knee lateral (3.03 and 2.99 mm), mid (3.81 and 3.74 mm), and medial (3.01 and 3.20 mm) were statistically thicker than in controls (right and left knee lateral 2.29 and 2.36 mm, mid 2.64 and 2.53 mm, medial 2.39 and 2.32 mm, respectively, p < .001). There was no significant correlation between FCT and sex hormones. In conclusion, patients with KS had thicker femoral cartilage. Relatively low testosterone levels in these patients and altered estrogen metabolism may hypothetically explain increased cartilage thickness in these patients.
Authors:
Mehmet Inci; Ozgur Akgul; Numan Baydilli; Oguz Ekmekcioglu; Salih Ozgöçmen
Related Documents :
19700875 - Retinal nerve fiber layer thickness analysis in suspected malingerers with optic disc t...
7898885 - Age differences in spatial contrast sensitivity are not the result of changes in subjec...
9112965 - Long-term grating acuity and visual-field development in preterm children who experienc...
2722435 - Adult vernier thresholds do not increase with age; vernier bias does.
24165155 - Comparative pharmacokinetics of factor viii and recombinant factor ix: for which coagul...
6800235 - Changes on computed cranial tomography with aging: intracranial fluid volume.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-6
Journal Detail:
Title:  American journal of men's health     Volume:  -     ISSN:  1557-9891     ISO Abbreviation:  Am J Mens Health     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101287723     Medline TA:  Am J Mens Health     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Ontogenic changes in human placental sodium iodide symporter expression.
Next Document:  Talking About Sexuality: Desire, Virility, and Intimacy in the Context of Prostate Cancer Associatio...