| Increased ALZ-50-reactive neurons in the brains of SIDS infants: an indicator of greater neuronal death? | |
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MedLine Citation:
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PMID: 2045627 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Brain tissue from 15 infants who had died from sudden infant death syndrome (SIDS) and 15 age-matched control infants was investigated for the presence of degenerating neurons using ALZ-50 immunocytochemical methods. Significantly increased numbers (P less than .0001) of ALZ-50-reactive neurons were found in SIDS infants compared to infants dying of known causes. The location and appearance of such ALZ-50-reactive neurons in SIDS may indicate that the initial degeneration of the central nervous system occurs early in the development of affected infants. |
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Authors:
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D L Sparks; J C Hunsaker |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of child neurology Volume: 6 ISSN: 0883-0738 ISO Abbreviation: J. Child Neurol. Publication Date: 1991 Apr |
Date Detail:
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Created Date: 1991-07-16 Completed Date: 1991-07-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8606714 Medline TA: J Child Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 123-7 Citation Subset: IM |
Affiliation:
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Department of Pathology, University of Kentucky Medical Center, Lexington. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Monoclonal Cell Count Cell Survival Humans Immunohistochemistry Infant Neurons / pathology* Sudden Infant Death / etiology, pathology* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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