Document Detail


Increase of the prostaglandin precursor, arachidonic acid, in amniotic fluid during spontaneous labour.
MedLine Citation:
PMID:  588506     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Concentrations of free arachidonic acid have been measured by gas liquid chromatography in amniotic fluid obtained during spontaneous labour at term. Levels of arachidonic acid ranged from 0.14 to 2.9 microgram/ml and increased significantly (P less than 0.01) with advancing cervical dilatation. Concentrations of arachidonic acid showed no significant relation to concentrations of either prostaglandin F or 13,14-dihydro-15-keto-prostaglandin F. These findings are discussed with respect to the role of arachidonic acid in the control of prostaglandin biosynthesis during human parturition.
Authors:
M J Keirse; B R Hicks; M D Mitchell; A C Turnbull
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  84     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1977 Dec 
Date Detail:
Created Date:  1978-02-23     Completed Date:  1978-02-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  937-40     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Amniotic Fluid / analysis*
Arachidonic Acids / analysis*
Female
Humans
Labor Stage, First*
Labor, Obstetric*
Pregnancy
Prostaglandins E / biosynthesis
Prostaglandins F / biosynthesis
Chemical
Reg. No./Substance:
0/Arachidonic Acids; 0/Prostaglandins E; 0/Prostaglandins F

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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