| Increase in size of the pulmonary autograft after the Ross operation in children: growth or dilation? | |
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MedLine Citation:
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PMID: 10612754 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: We sought to assess growth properties of the pulmonary autograft after the Ross operation in children. METHODS: Eight infants with critical aortic stenosis who underwent the Ross operation early in life (median age, 6.4 months) were followed up regarding the possible growth of the autograft. The pulmonary autograft was measured repeatedly by echocardiography during the follow-up, ranging from 6 months to 7 years (median, 5.2 years). Twelve normal children who served as control subjects were similarly followed from 3.9 to 5.8 years (median, 4.9 years). RESULTS: Somatic growth during the follow-up period was significant and was reflected in a doubling of the body surface area, which increased from 0.33 +/- 0.14 m(2) to 0.74 +/- 0.21 m(2). The proximal part of the autograft increased from 13.6 +/- 3.6 mm to 23.3 +/- 3.7 mm (mean +/- SD) and the distal part from 10.5 +/- 2.5 mm to 15.9 +/- 2.8 mm. Growth pattern of the autograft was analyzed by relating measured diameters to predicted normal diameters (ie, Z values). During the first year after the operation, the mean Z value of the proximal autograft increased from 0.2 to 2.2, indicating a more rapid increase than the predicted increase and was also significantly higher than that of the control group (P =.01). After the first year, Z-value changes in patients and control subjects were very similar. CONCLUSIONS: We thus conclude that the pulmonary autograft in the aortic position after the Ross operation does increase in size and that the pattern of this increase is suggestive of passive dilation in the early postoperative period, followed by normal active growth. |
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Authors:
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L Solymar; G Südow; D Holmgren |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of thoracic and cardiovascular surgery Volume: 119 ISSN: 0022-5223 ISO Abbreviation: J. Thorac. Cardiovasc. Surg. Publication Date: 2000 Jan |
Date Detail:
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Created Date: 2000-02-17 Completed Date: 2000-02-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376343 Medline TA: J Thorac Cardiovasc Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 4-9 Citation Subset: AIM; IM |
Affiliation:
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Section of Paediatric Cardiology, Department of Paediatrics, Sahlgrenska University Hospital, Göteborg, Sweden. laszlo.solymar@sahlgrenska.se |
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| MeSH Terms | |
Descriptor/Qualifier:
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Aortic Valve Stenosis
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surgery* Body Surface Area Case-Control Studies Dilatation, Pathologic / etiology, pathology Echocardiography Female Follow-Up Studies Heart Valve Prosthesis Implantation Humans Infant Male Pulmonary Valve / growth & development*, pathology, transplantation*, ultrasonography Recurrence Reoperation Survival Rate Time Factors Transplantation, Autologous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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