| Increase in serum alpha-fetoprotein without recurrent disease after hepatectomy for hepatocellular carcinoma. | |
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MedLine Citation:
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PMID: 7520014 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The case of a 58-year-old man with clinically-stable and compensated HBsAg-positive liver cirrhosis is reported. In April 1991, the patient underwent partial hepatectomy to treat a solitary 3.5 cm hepatocellular carcinoma (HCC), (Edmonson scale I), in the 5th liver segment. His serum alpha-fetoprotein (AFP) level was 24 ng/ml. After hepatectomy, the AFP level dropped to 8 ng/ml, but between the 4th and 12th month it rose gradually from 72 ng/ml to 4,520 ng/ml. Hepatic recurrence of HCC was excluded, but a 6 cm solitary metastasis (Edmonson scale III-IV) was detected on the right adrenal. Adrenalectomy was performed and two months later the patient is doing well and his AFP level is 51 ng/ml. The methodological approach to diagnosis, treatment and follow-up of HCC, and the relationship between AFP and liver and metastatic HCC, are discussed. |
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Authors:
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A Cristani; G Cioni; M De Santis; L Chianese; G Gozzetti; E Ventura |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 41 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 1994 Apr |
Date Detail:
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Created Date: 1994-09-13 Completed Date: 1994-09-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: GERMANY |
Other Details:
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Languages: eng Pagination: 137-9 Citation Subset: IM |
Affiliation:
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Clinica Medica III, University of Modena, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Gland Neoplasms
/
blood,
secondary,
surgery Adrenalectomy Carcinoma, Hepatocellular / blood*, secondary, surgery Hepatectomy* Humans Liver Neoplasms / blood*, pathology, surgery Male Middle Aged Neoplasm Recurrence, Local alpha-Fetoproteins / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/alpha-Fetoproteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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