| Increase in pre-shock pause caused by drug administration before defibrillation: an observational, full-scale simulation study. | |
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MedLine Citation:
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PMID: 20083336 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The importance of circulation during cardiopulmonary resuscitation has led to efforts to decrease time without chest compressions ("no-flow time"). The no-flow time from the interruption of chest compressions until defibrillation is referred to as the "pre-shock pause". A shorter pre-shock pause increases the chance of successful defibrillation. It is unclear whether drug administration affects the length of the pre-shock pause. Our study compares pre-shock pause with and without drug administration in a full-scale simulation. METHODS: This was an observational study in an ambulance including 72 junior physicians and a cardiac arrest scenario. Data were extracted by reviewing video recordings of the resuscitation. Sequences including defibrillation and/or drug administration were identified and assigned to one out of four categories: Defibrillation only (DC-only) and drug administration just prior to defibrillation (Drug+DC) for which the pre-shock pause was calculated, and drug administration alone (Drug-only) for which pre-drug time was calculated. RESULTS: DC-only sequences were identified in 68/72 simulations, Drug+DC in 24/72, and Drug-only in 33/72. Median pre-shock pauses were 18s (DC-only) and 32 (Drug+DC), and median pre-drug pause 6. The variation between pauses was statistically significant (p<<0.001). DC-only and Drug+DC sequences was found in 22/72 simulations. A statistically significant difference of 8s was found between the median pre-shock pauses: 17s (DC-only) and 25 (Drug+DC) (p<<0.001). For un-paired observations, the pre-shock pause increased with 78% and for paired observations 47%. CONCLUSIONS: Drug administration prior to defibrillation was associated with significant increases in pre-shock pauses in this full-scale simulation study. |
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Authors:
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Christian Bjerre H?yer; Erika F Christensen; Berit Eika |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-18 |
Journal Detail:
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Title: Resuscitation Volume: 81 ISSN: 1873-1570 ISO Abbreviation: Resuscitation Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-17 Completed Date: 2010-05-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0332173 Medline TA: Resuscitation Country: Ireland |
Other Details:
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Languages: eng Pagination: 343-7 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Centre for Medical Education, Faculty of Health Sciences, University of Aarhus, Aarhus N, Denmark. cbh@medu.au.dk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Coronary Syndrome
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complications,
therapy Cardiopulmonary Resuscitation / methods* Cardiotonic Agents / administration & dosage* Computer Simulation Coronary Circulation* Drug Administration Schedule Electric Countershock* Heart Arrest / etiology, physiopathology*, therapy* Heart Massage* Humans Injections, Intravenous Manikins Time Factors Ventricular Fibrillation / etiology, therapy Videotape Recording |
| Chemical | |
Reg. No./Substance:
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0/Cardiotonic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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