| Increase in normal placental weights related to increase in maternal body mass index. | |
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MedLine Citation:
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PMID: 18240079 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Reference values of normal placental weights are many decades old. Recently, a trend of increasing weights of normal placentas has been noted. We aimed to confirm this observation and to find any associated fetal and maternal factors. METHODS: Information on all live singleton deliveries that met our inclusion criteria was collected for the years 1995 and 2004 at Creighton University Medical Center in Omaha, Nebraska. This information was compared to the standards set forth in the older references. The Student's t-test and correlation-regression statistics were applied. RESULTS: The mean weight of the mature, term (37-42 weeks of gestation) placenta has increased significantly from 1995 to 2004 (499 g to 537 g, p = 0.02), as well as from the older standards (27% increase at 40 weeks of gestation). There has also been a significant increase in the maternal body mass index (BMI) from 1995 to 2004 (25.2 to 26.5, p = 0.02), which correlates with maternal weight gain during pregnancy, and fetal and placental weights. CONCLUSIONS: Normal placental weights have increased over the last decades and this may correlate with increasing maternal obesity. Further studies with larger populations are needed to confirm these findings. |
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Authors:
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Leah D Swanson; Chhanda Bewtra |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: 21 ISSN: 1476-7058 ISO Abbreviation: J. Matern. Fetal. Neonatal. Med. Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-02-01 Completed Date: 2008-04-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: United States |
Other Details:
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Languages: eng Pagination: 111-3 Citation Subset: IM |
Affiliation:
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Department of Pathology, Creighton University Medical Center, Omaha, NE 68131, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Body Mass Index* Female Fetal Weight Gestational Age Humans Organ Size Placenta / anatomy & histology* Pregnancy Weight Gain |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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