Document Detail

Increase in normal placental weights related to increase in maternal body mass index.
MedLine Citation:
PMID:  18240079     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Reference values of normal placental weights are many decades old. Recently, a trend of increasing weights of normal placentas has been noted. We aimed to confirm this observation and to find any associated fetal and maternal factors. METHODS: Information on all live singleton deliveries that met our inclusion criteria was collected for the years 1995 and 2004 at Creighton University Medical Center in Omaha, Nebraska. This information was compared to the standards set forth in the older references. The Student's t-test and correlation-regression statistics were applied. RESULTS: The mean weight of the mature, term (37-42 weeks of gestation) placenta has increased significantly from 1995 to 2004 (499 g to 537 g, p = 0.02), as well as from the older standards (27% increase at 40 weeks of gestation). There has also been a significant increase in the maternal body mass index (BMI) from 1995 to 2004 (25.2 to 26.5, p = 0.02), which correlates with maternal weight gain during pregnancy, and fetal and placental weights. CONCLUSIONS: Normal placental weights have increased over the last decades and this may correlate with increasing maternal obesity. Further studies with larger populations are needed to confirm these findings.
Leah D Swanson; Chhanda Bewtra
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  21     ISSN:  1476-7058     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-01     Completed Date:  2008-04-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  111-3     Citation Subset:  IM    
Department of Pathology, Creighton University Medical Center, Omaha, NE 68131, USA.
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MeSH Terms
Body Mass Index*
Fetal Weight
Gestational Age
Organ Size
Placenta / anatomy & histology*
Weight Gain

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