Document Detail

Increase in atrial natriuretic peptide in response to physical exercise.
MedLine Citation:
PMID:  2965008     Owner:  NLM     Status:  MEDLINE    
Circulating atrial natriuretic peptide (ANP) level was determined during physical exercise to investigate the correlation between changes in ANP level and heart rate increases. Six subjects exercised at a work level of 75% VO2max for 30 min, two also performed two successive exercises at 75% VO2max while two more exercised for longer at 55% VO2max. Plasma ANP levels and heart rate increased in all the exercising subjects. At the end of the exercise, the ANP level fell immediately, suggesting an immediate reduction in ANP secretion by the heart. Pre-exercise values were reached after 30 min. Successive exercises gave the same heart rate related ANP patterns without previous secretory episodes having any effect. These results lead to the conclusion that ANP intervenes in the cardiovascular adjustments to exercise.
M Follenius; G Brandenberger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of applied physiology and occupational physiology     Volume:  57     ISSN:  0301-5548     ISO Abbreviation:  Eur J Appl Physiol Occup Physiol     Publication Date:  1988  
Date Detail:
Created Date:  1988-05-02     Completed Date:  1988-05-02     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0410266     Medline TA:  Eur J Appl Physiol Occup Physiol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  159-62     Citation Subset:  IM    
Laboratoire de Physiologie et de Psychologie Environmentales, UM 32, C.N.R.S.-I.N.R.S., Strasbourg, France.
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MeSH Terms
Atrial Natriuretic Factor / metabolism*
Heart Rate
Oxygen Consumption
Physical Exertion*
Reg. No./Substance:
85637-73-6/Atrial Natriuretic Factor

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