Document Detail

An Increase in Right Atrial Magnetic Strength Is a Novel Predictor of Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation.
MedLine Citation:
PMID:  22473455     Owner:  NLM     Status:  Publisher    
Background: Differences in electrical properties between left and right atria (LA and RA) after pulmonary vein isolation (PVI) for atrial fibrillation (AF) are currently poorly understood. Magnetocardiograms were used to investigate the effect of PVI on bi-atrial magnetic field changes and their relationship to clinical outcomes. Methods and Results: This study included 71 patients undergoing PVI for paroxysmal AF. Magnetocardiograms were recorded at baseline and 1 day, 8 weeks, and 24 weeks after ablation. Peak magnitude of LA and RA segments on P waves was separately compared before and after PVI. During a 16-month post-ablation period, 53 (75%) patients were free from AF recurrences. LA magnetic strength in patients without recurrence persistently decreased for 24 weeks and was significantly lower at 8 weeks than that in patients with recurrence (1.28±0.69 vs. 1.74±0.71 pico-Tesla, P=0.02). RA magnetic strength in patients with recurrence persistently rose for 24 weeks and was significantly higher at 8 weeks than that in patients without recurrence (2.17±0.82 vs. 3.00±1.12 pico-Tesla, P=0.001). Multivariate analysis showed RA magnetic strength at 8 weeks to be the strongest predictor of AF recurrence (odds ratio=3.335; 95% confidence interval=1.181-9.416; P=0.02). Conclusions: PVI resulted in distinct changes in magnetic strength in both the LA and the RA. A persistent rise in RA magnetic strength might be a robust predictor of AF recurrence after ablation.
Yoko Sato; Kentaro Yoshida; Kuniomi Ogata; Takeshi Inaba; Hiroshi Tada; Yukio Sekiguchi; Yoko Ito; Tomoko Ishizu; Yoshihiro Seo; Iwao Yamaguchi; Akihiko Kandori; Kazutaka Aonuma
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-3
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  -     ISSN:  1347-4820     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Division of Cardiovascular Medicine, University of Tsukuba.
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