| Incorporation of unnatural amino acids for synthetic biology. | |
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MedLine Citation:
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PMID: 20024068 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The challenge of synthetic biology lies in the construction of artificial cellular systems. This requires the development of modular "parts" that can be integrated into living systems to elicit an artificial, yet programmed, response or function. The development of methods to engineer proteins bearing unnatural amino acids (UAAs) provides essential components that may address this challenge. Here we review the emerging strategies for incorporating UAAs into proteins with the endgame of engineering artificial cells and organisms. |
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Authors:
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Natalya Voloshchuk; Jin Kim Montclare |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review Date: 2009-09-04 |
Journal Detail:
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Title: Molecular bioSystems Volume: 6 ISSN: 1742-2051 ISO Abbreviation: Mol Biosyst Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-23 Completed Date: 2010-03-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101251620 Medline TA: Mol Biosyst Country: England |
Other Details:
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Languages: eng Pagination: 65-80 Citation Subset: IM |
Affiliation:
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Department of Chemical and Biological Sciences, Polytechnic Institute of New York University, Brooklyn, NY 11201, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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chemistry*,
genetics,
metabolism* Biology / methods* Models, Genetic Models, Theoretical Protein Engineering / methods* |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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