Document Detail

Incontinence induces stratum corneum vulnerability and impairs the skin barrier function in the perianal region.
MedLine Citation:
PMID:  17135734     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Incontinence leads to a reduced skin barrier function, while also increasing the risk of skin breakdown. AIM: To investigate the perianal skin barrier function of elderly patients with or without incontinence. METHODS: We compared the skin barrier function by investigating the skin hydration, the skin pH, the amount of ceramide and by making a dermatological skin inspection of the perianal region in patients with and without incontinence. RESULTS: Twenty-one incontinent patients (70.0%) showed a glossy skin, which indicates impairment of the skin barrier while none of the patients in the continence group did so. In the incontinence group, those who had a glossy skin showed a significantly greater skin pH and total amount of ceramide than those with a normal skin (p = 0.0099, p = 0.0179, respectively). CONCLUSIONS: These results demonstrate that a glossy skin may be a useful indicator of a reduced perianal skin barrier function.
Gojiro Nakagami; Hiromi Sanada; Atsuko Kitagawa; Etsuko Tadaka; Takeo Maekawa; Takashi Nagase; Chizuko Konya
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Dermatology (Basel, Switzerland)     Volume:  213     ISSN:  1018-8665     ISO Abbreviation:  Dermatology (Basel)     Publication Date:  2006  
Date Detail:
Created Date:  2006-11-30     Completed Date:  2007-02-16     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9203244     Medline TA:  Dermatology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  293-9     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2006 S. Karger AG, Basel.
Department of Gerontological Nursing/Wound Care Management, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
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MeSH Terms
Aged, 80 and over
Anal Canal
Body Water / chemistry
Ceramides / analysis
Cross-Sectional Studies
Hydrogen-Ion Concentration
Perineum / pathology,  physiopathology*
Skin / chemistry,  pathology
Skin Physiological Phenomena*
Urinary Incontinence / physiopathology*
Water Loss, Insensible / physiology
Reg. No./Substance:

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