| Incomplete dominant osteochondrodysplasia in heterozygous Scottish Fold cats. | |
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MedLine Citation:
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PMID: 18339089 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This report describes an autosomal incomplete dominant pattern of inheritance for osteochondrodysplasia in the Scottish Fold cats. A three-generation pedigree was analysed. Cats with folded ears were mated with cats with normal ears. All cats with folded ears, which were presumably heterozygous for the mutated allele, developed osteochondrodysplasia in distal fore- and hindlimbs but not in other bones, including the tail in which bone deformity had been demonstrated in previous studies. The severity of the skeletal lesions of osteochondrodysplasia was different in each affected cat. Most of the cats with severe osteochondrodysplasia showed some clinical signs, but cats with mild disease were clinically unaffected. All Scottish Fold-related cats with folded-ear phenotype, even if heterozygotes, suffered from some degree of osteochondrodysplasia of the distal limbs. |
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Authors:
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M Takanosu; T Takanosu; H Suzuki; K Suzuki |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of small animal practice Volume: 49 ISSN: 0022-4510 ISO Abbreviation: J Small Anim Pract Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-03-14 Completed Date: 2008-06-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0165053 Medline TA: J Small Anim Pract Country: England |
Other Details:
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Languages: eng Pagination: 197-9 Citation Subset: IM |
Affiliation:
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Nasunogahara Animal Clinic 2-3574-98, Asaka, Ohtawara, Tochigi 324-0043, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cartilage, Articular / pathology Cat Diseases / genetics*, pathology, radiography Cats Ear, External / anatomy & histology Female Forelimb / pathology Genetic Predisposition to Disease Hindlimb / pathology Lameness, Animal Male Osteochondrodysplasias / genetics, pathology, radiography, veterinary* Pedigree* Phenotype Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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