Document Detail

Incidental unruptured intracranial aneurysms in patients with acute ischemic stroke.
MedLine Citation:
PMID:  18984951     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The management and clinical prognosis of incidental intracranial aneurysms in acute ischemic stroke patients have been understudied. We investigated the clinical outcome of acute ischemic stroke subjects with incidentally found intracranial aneurysms. METHODS: We consecutively included acute ischemic stroke patients within 7 days of onset. Their demographics, risk factors, stroke subtypes, antithrombotics use and modified Rankin scale (mRS) at 3 months after stroke were obtained. CT or MR angiography was used to diagnose the intracranial aneurysms. The development of an aneurysmal rupture was checked during the following 3 months. RESULTS: Incidental intracranial aneurysms were found in 17 (6.6%) of the 258 patients. The female sex and old age were associated with the presence of incidental intracranial aneurysms (p = 0.001, 0.032). The most common site of aneurysm was at the distal internal carotid artery (n = 9), followed by the middle cerebral artery (n = 6). The diameters of the aneurysms ranged from 2.09 to 8.06 mm. All the participants except 1 who had cancer were taking antiplatelet agents. No aneurysmal rupture or subarachnoid hemorrhage happened until 3 months after stroke.There was no significant difference in excellent outcome (3-month mRS = 0, 1) between the patients with an aneurysm and those without (28.6 vs. 53.4%, p = 0.097). CONCLUSION: There was no rupture of the incidentally found aneurysms in the patients with acute ischemic stroke during their first 3 months. The 3-month mRS was not affected by the presence of incidental intracranial aneurysm. A large cohort study and long-term follow-up are required.
Yoon-Sang Oh; Seung-Jae Lee; Young-Min Shon; Dong Won Yang; Beum Saeng Kim; A-Hyun Cho
Publication Detail:
Type:  Journal Article     Date:  2008-11-04
Journal Detail:
Title:  Cerebrovascular diseases (Basel, Switzerland)     Volume:  26     ISSN:  1421-9786     ISO Abbreviation:  Cerebrovasc. Dis.     Publication Date:  2008  
Date Detail:
Created Date:  2008-12-04     Completed Date:  2009-03-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9100851     Medline TA:  Cerebrovasc Dis     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  650-3     Citation Subset:  IM    
Copyright Information:
2008 S. Karger AG, Basel.
Department of Neurology, Catholic University of Korea, St. Mary's Hospital, Seoul, South Korea.
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MeSH Terms
Acute Disease
Aged, 80 and over
Aneurysm, Ruptured / epidemiology
Brain Ischemia / complications*,  therapy
Carotid Artery Diseases / complications
Carotid Artery, Internal / pathology
Diffusion Magnetic Resonance Imaging
Disease Progression
Follow-Up Studies
Hypertension / complications
Incidental Findings
Intracranial Aneurysm / complications*,  radiography
Middle Aged
Platelet Aggregation Inhibitors / therapeutic use
Risk Factors
Tomography, X-Ray Computed
Treatment Outcome
Reg. No./Substance:
0/Platelet Aggregation Inhibitors

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