| Incidental radiological findings on brain magnetic resonance imaging in first-episode psychosis and chronic schizophrenia. | |
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MedLine Citation:
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PMID: 12366466 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate whether patients with first-episode psychosis or chronic schizophrenia have an increased incidence of magnetic resonance imaging (MRI) brain abnormalities compared with control subjects. METHOD: Totally 340 clinical MRI reports [Controls (n=98), first-episode psychoses (n=152), chronic schizophrenia (n=90)] were reported by a neuroradiologist blind to diagnosis and subsequently categorized using referral criteria (immediate, urgent, routine or no referral). RESULTS: Thirty percent of all scans were reported by a neuroradiologist as abnormal, but the majority required no referral. Patients with chronic schizophrenia were more likely to have clinically significant abnormal scans than patients with first episode psychosis or control subjects. In four patients the MRI findings led to the discovery of previously unsuspected pathology. CONCLUSION: Patients with chronic schizophrenia have an increased prevalence of incidental brain abnormalities. A small proportion of patients with chronic schizophrenia and first-episode psychosis benefitted directly from MRI scanning. |
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Authors:
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D I Lubman; D Velakoulis; P D McGorry; D J Smith; W Brewer; G Stuart; P Desmond; B Tress; C Pantelis |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta psychiatrica Scandinavica Volume: 106 ISSN: 0001-690X ISO Abbreviation: Acta Psychiatr Scand Publication Date: 2002 Nov |
Date Detail:
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Created Date: 2002-10-07 Completed Date: 2003-03-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370364 Medline TA: Acta Psychiatr Scand Country: Denmark |
Other Details:
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Languages: eng Pagination: 331-6 Citation Subset: IM |
Affiliation:
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Cognitive Neuropsychiatry Research & Academic Unit, The University of Melbourne & Sunshine Hospital, Melbourne, Australia. dan.lubman@mh.org.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain / pathology* Female Humans Incidental Findings Magnetic Resonance Imaging* Male Psychotic Disorders / diagnosis* Schizophrenia / diagnosis* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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