Document Detail


Incidental MRI lesions suggestive of multiple sclerosis in asymptomatic patients in Karachi, Pakistan.
MedLine Citation:
PMID:  20971756     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to identify asymptomatic patients with brain MRI lesions suggestive of multiple sclerosis (MS) in a low-prevalence area of Pakistan. Brain MRIs for 864 patients were reviewed at the Aga Khan University (Karachi, Pakistan) during an 8-month period of 2006 and 2007 to identify patients with lesions suggestive of MS. The lesions were characterised based on modified Barkhof criteria. Six (two females) (0.7%) of 864 patients fulfilled brain MRI criteria suggestive of MS. The mean number of MRI lesions (total lesions on T2) were 9 (range 5-14). Although Pakistan is considered a low-prevalence area for MS, 0.7% of brain MRI scans in patients without clinical MS symptoms showed lesions fulfilling brain MRI criteria of MS.
Authors:
M Wasay; F Rizvi; M Azeemuddin; A Yousuf; S Fredrikson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-10-22
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  82     ISSN:  1468-330X     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-14     Completed Date:  2011-01-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  83-5     Citation Subset:  IM    
Affiliation:
Department of Neurology, Aga Khan University, Karachi, Pakistan. mohammad.wasay@aku.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Evoked Potentials, Visual / physiology
Female
Humans
Magnetic Resonance Imaging
Male
Multiple Sclerosis / diagnosis,  epidemiology,  pathology*
Pakistan / epidemiology
Retrospective Studies
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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