Document Detail


Incidental Aortic Valve Calcification on CT Scans Significance for Bicuspid and Tricuspid Valve Disease.
MedLine Citation:
PMID:  22104287     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
RATIONALE AND OBJECTIVES: The aim of this study was to evaluate the role of incidental aortic valve calcification on routine computed tomographic scans as a marker for stenosis, as assessed by echocardiography, in patients with bicuspid aortic valve (BAV) and tricuspid aortic valve. MATERIALS AND METHODS: Computed tomographic and echocardiographic studies were retrospectively reviewed for 182 consecutive, unselected patients and 426 patients identified by a record search for "aortic valve calcification." Location and severity of valve calcification were correlated with aortic valve morphology and stenosis. Differences between subgroups were assessed using χ(2) or Fisher's exact tests. RESULTS: In unselected patients, calcification was present in 25.8% with tricuspid aortic valves (46 of 178) and 75% (three of four) with BAV. In patients selected for valve calcification, the average age of those with tricuspid aortic valves (n = 395) was 14.3 years older than those with BAV (n = 31). Patients with BAV were more likely to have severe calcification (87% vs 50%, P < .001), and if severe calcification was present, it was more likely to involve only the valve leaflets (41% vs 9%, P < .001) and result in aortic stenosis (85% vs 58%, P = .006). Patients aged < 60 years with severe calcification were more likely to have BAV (56% vs 7%; odds ratio, 7.9; 95% confidence interval, 3.4-18.7). CONCLUSIONS: Aortic valve calcification was found 14 years earlier in patients with BAV and was more severe and strongly linked to aortic stenosis. Valve calcification on computed tomographic scans should be considered a marker for BAV if found before the seventh decade.
Authors:
Michael D Hope; Thomas H Urbania; John-Paul J Yu; Sam Chitsaz; Elaine Tseng
Related Documents :
22122377 - Repair of kommerell's diverticulum with aberrant left subclavian artery in an elderly p...
22163127 - Perimembranous ventricular septal defect with aneurysm: two options for transcatheter c...
18954627 - The influence of seasonal variation on cardiac surgery: a time-related clinical outcome...
22110507 - Single coronary artery with anomalous rising of the right coronary artery: a rare coron...
18751467 - Development of aortic valve sclerosis or stenosis in rabbits: role of cholesterol and c...
7714877 - Prosthetic vascular graft and autogenous vein graft with free-tissue transfer in attemp...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-18
Journal Detail:
Title:  Academic radiology     Volume:  -     ISSN:  1878-4046     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9440159     Medline TA:  Acad Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 AUR. Published by Elsevier Inc. All rights reserved.
Affiliation:
Department of Radiology, University of California, San Francisco, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143-0628.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Caudal Image Contrast Inversion in MPRAGE at 7 Tesla Problem and Solution.
Next Document:  Hyperpolarized (3)He Magnetic Resonance Functional Imaging Semiautomated Segmentation.