Document Detail


[Incidence, resource use and costs associated with postherpetic neuralgia: a population-based retrospective study].
MedLine Citation:
PMID:  23055426     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To determine the incidence rate, the treatment administered and the use of health resources and health, and their respective costs in patients with postherpetic neuralgia (PHN).
PATIENTS AND METHODS: We performed an observational design, made from retrospective review of patient records from six primary care centers and one hospital. All patients > 30 years consulting for PHN between 1/1/2007 and 31/12/2010 were included. Prepared two study groups according to presence / absence of PHN. Follow up was for one year.
MAIN MEASURES: socio-demographic, treatment and co-morbidity. The cost model differed direct healthcare costs (primary care/specialist) and indirect (productivity).
STATISTICAL ANALYSIS: logistic regression models and analysis of covariance (p < 0.05).
RESULTS: 1506 patients were recruited, age: 61.2 years female: 59.2%. 15.1% (n = 228, 95% CI = 8.1-22.1%) had a PHN (incidence rate: 0.8/1,000 inhabitants/year; 95% CI = 0.7-0.9/1,000 population/year), and increased with age (≥ 65 years: 19.7%). The PHN was principally associated with: psychosis (OR = 3.9), dementia (OR = 2.3), depression (OR = 1.8) and age (OR = 1.1), p < 0.03. Drugs use was higher (5.3 vs. 3.3; p < 0.001). The cost in primary care was 63.1% and 24.7% indirect. Total cost €1827.1 vs. €457.5 (p = 0.003), respectively, due to higher labour productivity losses (€692.2 vs. €62.4) and health costs (€1135 vs. €395.1); p < 0.001. All cost components maintained these differences.
CONCLUSIONS: PHN is a frequent complication. These patients have a significant economic burden. The cost increases with age.
Authors:
Antonio Sicras-Mainar; Ruth Navarro-Artieda; Jordi Ibáñez-Nolla; Julián Pérez-Ronco
Publication Detail:
Type:  English Abstract; Journal Article; Multicenter Study    
Journal Detail:
Title:  Revista de neurologia     Volume:  55     ISSN:  1576-6578     ISO Abbreviation:  Rev Neurol     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-11     Completed Date:  2013-04-05     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  7706841     Medline TA:  Rev Neurol     Country:  Spain    
Other Details:
Languages:  spa     Pagination:  449-61     Citation Subset:  IM    
Vernacular Title:
Incidencia, uso de recursos y costes asociados a la neuralgia postherpetica: estudio retrospectivo de base poblacional.
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MeSH Terms
Descriptor/Qualifier:
Absenteeism
Adult
Aged
Ambulatory Care / economics,  statistics & numerical data
Comorbidity
Cost of Illness
Drug Utilization / statistics & numerical data
Female
Health Care Costs / statistics & numerical data
Health Expenditures / statistics & numerical data
Hospital Costs / statistics & numerical data
Hospitals, Urban / economics,  statistics & numerical data
Humans
Incidence
Male
Middle Aged
Models, Economic
Neuralgia, Postherpetic / drug therapy,  economics,  epidemiology*
Prescription Fees / statistics & numerical data
Registries
Retrospective Studies
Spain / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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