Document Detail


Incidence and prevalence rate estimation of GH treatment exposure in Piedmont pediatric population in the years 2002-2004: Data from the GH Registry.
MedLine Citation:
PMID:  16794367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The aim of this study is to estimate the annual incidence and prevalence rate of the GH treatment exposure in patients under the age of 18 treated for hypopituitarism or isolated GH deficiency (GHD) in Piedmont, during the period January 1, 2002 to December 31, 2004. METHODS: The selection criteria for recombinant human GH (rhGH) treatment in childhood were approved by the Ministry of Health in Italy in the yr 1998. The present analysis is based on data from the Registry of subjects receiving GH therapy (GH Registry) made up of the 918 pediatric patients (age <18 yr) with a diagnosis of GHD (excluding Prader-Willi and Turner syndromes and other conditions), diagnosed in the period January 1, 2002 - December 31, 2004. The case series has been described as regards the number of cases per year of diagnosis; the prevalence and incidence rates, calculated per 10,000 (per ten thousand) inhabitants, are given for each year of the study period. RESULTS: The prevalence rate increases slightly from 8.62 per thousand in 2002 to 9.44 per thousand in 2004 and the incidence rates estimated were 2.49 per ten thousand, 1.86 per ten thousand and 1.97 per ten thousand in the yr 2002, 2003 and 2004, respectively. CONCLUSION: The Piedmont GH Registry represents the first database available in Italy and could set an example for the other Italian regions as well.
Authors:
G Migliaretti; G Aimaretti; A Borraccino; J Bellone; S Vannelli; A Angeli; L Benso; G Bona; F Camanni; C de Sanctis; A Ravaglia; F Cavallo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of endocrinological investigation     Volume:  29     ISSN:  0391-4097     ISO Abbreviation:  J. Endocrinol. Invest.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-06-23     Completed Date:  2006-08-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806594     Medline TA:  J Endocrinol Invest     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  438-42     Citation Subset:  IM    
Affiliation:
Department of Public Health and Microbiology, University of Turin, Turin, Italy. giuseppe.migliaretti@unito.it
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Human Growth Hormone / deficiency*,  therapeutic use*
Humans
Hypopituitarism / drug therapy*,  epidemiology
Incidence
Italy / epidemiology
Prevalence
Registries*
Chemical
Reg. No./Substance:
12629-01-5/Human Growth Hormone
Comments/Corrections
Comment In:
J Endocrinol Invest. 2006 May;29(5):391-2   [PMID:  16794360 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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