Document Detail


Incidence and prevalence of juvenile idiopathic arthritis in Catalonia (Spain).
MedLine Citation:
PMID:  20858139     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To ascertain the incidence and prevalence of juvenile idiopathic arthritis (JIA) in Catalonia (autonomous region in northeast Spain), examined according to the currently established disease subtypes.
METHODS: Before initiating the study, we conducted an educational programme on paediatric rheumatology, addressed to all general paediatricians in Catalonia. A 2-year (2004-2006), prospective, population-based study was then carried out to determine the incidence of JIA. Prospective and retrospective data retrieval was performed to calculate prevalence. The International League of Associations for Rheumatology (ILAR, Edmonton revision) classification criteria were applied.
RESULTS: Over the study period, 145 new cases of JIA were diagnosed. The mean annual incidence was 6.9/10⁵ children aged less than 16 years (range 5.8-8.1 years; 9.0 years for girls and 4.8 years for boys). On separate analysis of patients ≤ 6 and > 6 years, the distribution in younger children was found to be similar for both girls and boys, whereas in older children, most girls belonged to the oligoarthritis and polyarthritis subgroups, and boys to the enthesitis-related arthritis and undifferentiated subgroups. The calculated prevalence of JIA (31 October 2006) was 39.7 (36.1-43.7)/10⁵ children younger than 16. The relative risk of girls having JIA was 2.1 [95% confidence interval (CI) 1.7-2.7, p < 0.001]. In 70% of patients, the diagnosis was established before the age of 7. Subgroup distribution of prevalent cases mirrored that of incident cases.
CONCLUSION: This is the first population-based study on the epidemiology of JIA in Catalonia. Incidence and prevalence rates are lower than those reported for several areas in Nordic countries of Europe. Oligoarthritis was the most common subtype.
Authors:
C Modesto; J Antón; B Rodriguez; R Bou; C Arnal; J Ros; X Tena; C Rodrigo; I Rotés; E Hermosilla; P Barceló
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-09-21
Journal Detail:
Title:  Scandinavian journal of rheumatology     Volume:  39     ISSN:  1502-7732     ISO Abbreviation:  Scand. J. Rheumatol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-29     Completed Date:  2010-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0321213     Medline TA:  Scand J Rheumatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  472-9     Citation Subset:  IM    
Affiliation:
Department of Rheumatology, University Hospital Vall d'Hebron, Barcelona, Spain. cmodesto@vhebron.net
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Arthritis, Juvenile Rheumatoid / diagnosis,  epidemiology*
Child
Child, Preschool
Female
HLA-B27 Antigen / analysis
Humans
Incidence
Infant
Male
Prevalence
Prospective Studies
Retrospective Studies
Sex Factors
Spain / epidemiology
Chemical
Reg. No./Substance:
0/HLA-B27 Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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