Document Detail

Incidence, predictors, origin and prevention of early and late neurological events after transcatheter aortic valve implantation (TAVI): a comprehensive review of current data.
MedLine Citation:
PMID:  23292438     Owner:  NLM     Status:  Publisher    
Transcatheter aortic valve implantation (TAVI) is a novel treatment option for patients with severe, symptomatic aortic valve stenosis considered inoperable or at high risk for surgical aortic valve replacement. Despite rapid adoption of this technology into clinical application, however, recent randomized controlled clinical trials have raised safety concerns regarding an increased risk of neurological events with TAVI compared to both medical treatment and conventional, surgical aortic valve replacement. Moreover, neuro-imaging studies have revealed an even higher incidence of new, albeit clinically silent cerebral lesions as a surrogate for procedural embolization. In this article, we review currently available data on the incidence, timing, predictors, prognostic implications and potential mechanisms of neurological events after TAVI.
Philipp Kahlert; Fadi Al-Rashid; Björn Plicht; Heike Hildebrandt; Polykarpos Patsalis; Karim El Chilali; Daniel Wendt; Matthias Thielmann; Lars Bergmann; Eva Kottenberg; Marc Schlamann; Holger Eggebrecht; Heinz Jakob; Gerd Heusch; Thomas Konorza; Raimund Erbel
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-6
Journal Detail:
Title:  Journal of thrombosis and thrombolysis     Volume:  -     ISSN:  1573-742X     ISO Abbreviation:  J. Thromb. Thrombolysis     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9502018     Medline TA:  J Thromb Thrombolysis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Cardiology, West-German Heart Center Essen, Essen University Hospital, University Duisburg-Essen, Hufelandstr.55, 45122, Essen, Germany,
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