Document Detail


Incidence, population, and survival of cystic fibrosis in the UK, 1968-95. UK Cystic Fibrosis Survey Management Committee.
MedLine Citation:
PMID:  9496181     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The UK Cystic Fibrosis Survey holds data on all people resident in the UK who were diagnosed as having cystic fibrosis and born either since 1968 or before 1968 and alive in 1977. Thus, incidence may be reported from 1968 and prevalence from 1977. The previous estimates are updated to the end of 1995 from data held in the database on 23 August 1996. The incidence is now calculated as one in 2415 live births. The 1992 mid-year population was 6500 people with 65% aged under 16 years. Births outnumber deaths by 160 per year, which suggests a population of 7750 by the year 2000, with all the increase being in the adult age range. The survival of successive cohorts continues to be better than earlier cohorts, the linear descent of the curves is still evident. The infant mortality rate for cystic fibrosis is now under 20 per thousand per year and early childhood mortality is under five per thousand per year. The crude mortality rate for 1995 was 21 per thousand per year, but the standardised mortality ratio was about 3300.
Authors:
J A Dodge; S Morison; P A Lewis; E C Coles; D Geddes; G Russell; J M Littlewood; M T Scott
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  77     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-03-16     Completed Date:  1998-03-16     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  493-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Child Health, Queen's University of Belfast.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Child, Preschool
Cystic Fibrosis / epidemiology*,  mortality
Female
Great Britain / epidemiology
Humans
Incidence
Infant
Infant Mortality
Infant, Newborn
Male
Prevalence
Survival Rate
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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