Document Detail


Incidence and outcomes of out-of-hospital cardiac arrest with shock-resistant ventricular fibrillation: Data from a large population-based cohort.
MedLine Citation:
PMID:  20684862     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: The increasing survival rates after out-of-hospital cardiac arrests (OHCA) are due mainly to improvements in the first 3 steps of the chain of survival. The aim of this study was to describe the temporal trends of OHCA incidence and outcomes with shock-resistant ventricular fibrillation (VF) requiring advanced life support procedures. METHODS: All our subjects were persons aged 18 years or more who had suffered OHCA of presumed cardiac etiology, were witnessed by bystanders, treated by emergency medical service (EMS), and had VF as initial rhythm. Our study was conducted in Osaka Prefecture, Japan from May 1, 1998 through December 31, 2006. Data were collected by EMS personnel using an Utstein-style database. We evaluated the temporal trends of incidence and outcomes of shock-resistant VF. RESULTS: During the study period, there were 8782 witnessed OHCA cases of presumed cardiac etiology. Among them, 1733 had VF as an initial rhythm, 392 of whom were shock-resistant. While the age-adjusted annual incidence of witnessed VF increased from 2.0 to 3.3 per 100,000 inhabitants, that of shock-resistant VF underwent little change during the study period. The proportion of shock-resistant VF among witnessed VF decreased from 37.0% to 19.0%. Neurologically intact 1-month survival rates after shock-resistant VF remained low at 5.6% even in 2006. CONCLUSION: The actual incidence of shock-resistant VF has remained unchanged, and their outcomes continue to be dismal. Further efforts are required to reduce the mortality rates of such shock-resistant VF to achieve improved survival after OHCA.
Authors:
Tomohiko Sakai; Taku Iwami; Osamu Tasaki; Takashi Kawamura; Yasuyuki Hayashi; Hiroshi Rinka; Yasuo Ohishi; Tomoyoshi Mohri; Masafumi Kishimoto; Tatsuya Nishiuchi; Kentaro Kajino; Hisatake Matsumoto; Toshifumi Uejima; Masahiko Nitta; Chizuka Shiokawa; Hisashi Ikeuchi; Atsushi Hiraide; Hisashi Sugimoto; Yasuyuki Kuwagata
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-5-29
Journal Detail:
Title:  Resuscitation     Volume:  -     ISSN:  1873-1570     ISO Abbreviation:  -     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-8-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0332173     Medline TA:  Resuscitation     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita City, Osaka 565-0871, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  What is behavioral activation? A review of the empirical literature.
Next Document:  RNAi targeting EZH2 inhibits tumor growth and liver metastasis of pancreatic cancer in vivo.