Document Detail

Incidence of neonatal herpes simplex virus infections in a managed-care population.
MedLine Citation:
PMID:  17413535     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the incidence of possible neonatal herpes simplex virus (HSV) infections, HSV infection status of women with infected infants, and use of measures to reduce risk of HSV transmission to the neonate in a large US managed-care population. STUDY DESIGN: Retrospective analysis of administrative claims from the Integrated Health Care Information Services National Managed Care Benchmark database. RESULTS: Of 233,487 infants born to 252,474 mothers from January 1997 to June 2002, the numbers assigned an ICD-9 code reflecting possible neonatal HSV infection </=30 and </=90 days of birth were 178 (0.08%) and 338 (0.15%), respectively. Of the 338 mothers delivering infants with possible neonatal HSV </=90 days postnatally, 12% had a prior HSV diagnosis, 5% were prescribed an antiviral medication during the study period, and 3% used antiviral medication and had a cesarean delivery. CONCLUSION: These results support national surveillance of neonatal HSV to better define its incidence, strengthen health policies, and improve prevention and treatment.
Richard Whitley; Elizabeth Anne Davis; Nittaya Suppapanya
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Sexually transmitted diseases     Volume:  34     ISSN:  0148-5717     ISO Abbreviation:  Sex Transm Dis     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-28     Completed Date:  2007-10-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7705941     Medline TA:  Sex Transm Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  704-8     Citation Subset:  IM    
Department of Pediatrics, Microbiology, Medicine and Neurosurgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
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MeSH Terms
Diagnosis-Related Groups / statistics & numerical data
Herpes Simplex / epidemiology*,  etiology,  prevention & control*,  transmission
Infant, Newborn
Infectious Disease Transmission, Vertical / statistics & numerical data*
Managed Care Programs
Medical Records
Pregnancy Complications, Infectious / epidemiology*,  etiology,  prevention & control*
Prenatal Care
Retrospective Studies
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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