| Incidence of late lepra reaction among multibacillary leprosy patients after MDT. | |
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MedLine Citation:
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PMID: 7730714 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Multidrug therapy (MDT) recommended by the World Health Organization (WHO) had been administered in 1982 to a cohort of multibacillary (MB) leprosy patients. Treatment was administered for a minimum period of 2 years or until skin-smear negativity for acid-fast bacilli was achieved (whichever was later). Among 980 MB leprosy patients who completed treatment, 11 patients (1.1%) experienced lepra reactions during surveillance. Probable predictive factors are discussed. The incidence of lepra reaction seemed to be three times more common in borderline (BL) leprosy than in lepromatous (LL) leprosy. The majority of these events occurred during the first 3 years of surveillance. All of these episodes were treated with steroids without antileprosy chemotherapy. None of these patients was confirmed as experiencing a relapse during the subsequent period of surveillance. |
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Authors:
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P Vijayakumaran; N Manimozhi; K Jesudasan |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association Volume: 63 ISSN: 0148-916X ISO Abbreviation: Int. J. Lepr. Other Mycobact. Dis. Publication Date: 1995 Mar |
Date Detail:
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Created Date: 1995-05-30 Completed Date: 1995-05-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8505819 Medline TA: Int J Lepr Other Mycobact Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 18-22 Citation Subset: IM |
Affiliation:
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Branch of Epidemiology and Leprosy Control, Schieffelin Leprosy Research and Training Center, Karigiri, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Colony Count, Microbial Drug Therapy, Combination Humans Incidence Leprostatic Agents / therapeutic use* Leprosy, Borderline / complications, drug therapy*, microbiology Leprosy, Lepromatous / complications, drug therapy*, microbiology Mycobacterium leprae / growth & development Recurrence |
| Chemical | |
Reg. No./Substance:
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0/Leprostatic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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