Document Detail


Incidence and impact of risk factors in critically ill trauma patients.
MedLine Citation:
PMID:  16369714     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is a paucity of data describing the incidence of pre-existing diseases or risk factors and their effects in trauma patients. We conducted a prospective study to determine the incidence of such factors in critically ill trauma patients and to evaluate their impact on outcome. The study, performed over a 2-year period, examined the hospital course of all trauma patients admitted to the ICU. Multiple risk factors were evaluated and analyzed via multivariate regression analysis. Outcome was evaluated by infection rate, hospital length of stay, ventilator days, and mortality matched for age and Injury Severity Score (ISS). A total of 1172 patients (73% blunt injury) were enrolled over the study period. Of these, 873 (74.5%) were male. The mean age was 42.5 years with an ISS of 19.8. Tobacco use (24%) was the most common risk factor identified, followed by hypertension (HTN, 17%), coronary artery disease (9%), chronic obstructive pulmonary disease (COPD)/reactive airway disease (4%), non-insulin-dependent diabetes (NIDDM) (4%), insulin-dependent diabetes (IDDM) (3.2%), cancer (3%), liver disease (2%), and HIV/AIDS (1.4%). Of these risk factors, IDDM was found to be an independent risk factor for infection (0.004) and ventilator days (0.047), increasing age was found to be an independent risk factor for hospital length of stay (0.023) and mortality (<0.001), and HTN was found to be an independent risk factor for increased ventilator days (0.04). In addition, COPD/reactive airway disease was found to be an independent predictor of ventilator days, infection, and ICU days (P < 0.05). Thus, increased age, IDDM, COPD, and HTN are most predictive of outcome in critically ill trauma patients. With our aging population it is becoming increasingly important to identify pre-existing risk factors on admission in order to minimize their effects on outcome.
Authors:
Grant V Bochicchio; Manjari Joshi; Kelly Bochicchio; Diane Shih; W Meyer; Thomas M Scalea
Related Documents :
22131554 - Exposure to metal-working fluids in the automobile industry and the risk of male germ c...
1486094 - Respiratory effects of cocaine freebasing among habitual cocaine users.
1443304 - Passive smoking and lung cancer in nonsmoking women.
21676914 - Olive oil consumption, plasma oleic acid, and stroke incidence: the three-city study.
21054614 - The step into action study: a peer-based, personal risk network-focused hiv prevention ...
16712444 - Young adult smoker risk perceptions of traditional cigarettes and nontraditional tobacc...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of surgery     Volume:  30     ISSN:  0364-2313     ISO Abbreviation:  World J Surg     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-10     Completed Date:  2006-03-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7704052     Medline TA:  World J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  114-8     Citation Subset:  IM    
Affiliation:
The R Adams Cowley Shock Trauma Center, Division of Clinical and Outcomes Research, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, Maryland 21201, USA. gbochicchio@umm.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Critical Illness
Humans
Injury Severity Score
Length of Stay
Middle Aged
Multivariate Analysis
Prospective Studies
Risk Factors
Wounds and Injuries / epidemiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Changing treatment strategy for gastrinoma in patients with Zollinger-Ellison syndrome.
Next Document:  Significance of extensive surgery including resection of the pancreas head for the treatment of gall...