Document Detail


Incidence of haemoglobinopathies detected through neonatal screening in the United Arab Emirates.
MedLine Citation:
PMID:  16602448     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In January 2002, a pilot programme of neonatal screening for sickle cell disease was launched in the United Arab Emirates (UAE) in 3 districts of Abu Dhabi emirate. This paper reports the incidence of sickle cell diseases, other haemoglobinopathies and haemoglobinopathy carriers over a 12-month period using high performance liquid chromatography as a primary screening method. The overall incidence of sickle cell disease among 22 200 screened neonates was 0.04% (0.07% for UAE citizens and 0.02% for non-UAE citizens). The incidence of sickle cell trait was 1.1% overall (1.5% for UAE citizens and 0.8% for non-UAE citizens). Universal neonatal screening for sickle cell haemoglobin at the national level should be considered.
Authors:
H Al Hosani; M Salah; H M Osman; H M Farag; S M Anvery
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Eastern Mediterranean health journal = La revue de santé de la Méditerranée orientale = al-Majallah al-ṣiḥḥīyah li-sharq al-mutawassiṭ     Volume:  11     ISSN:  1020-3397     ISO Abbreviation:  East. Mediterr. Health J.     Publication Date:  2005 May 
Date Detail:
Created Date:  2006-04-10     Completed Date:  2006-05-04     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  9608387     Medline TA:  East Mediterr Health J     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  300-7     Citation Subset:  IM    
Affiliation:
Central Department of Maternal and Child Health, Ministry of Health, Abu-Dhabi, United Arab Emirates.
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MeSH Terms
Descriptor/Qualifier:
Anemia, Sickle Cell* / diagnosis,  epidemiology,  genetics
Birth Rate
Chromatography, High Pressure Liquid
Follow-Up Studies
Genetic Counseling
Genetic Testing* / methods,  utilization
Health Services Needs and Demand
Hemoglobin C Disease / diagnosis,  epidemiology,  genetics
Hemoglobin E
Hemoglobinopathies* / diagnosis,  epidemiology,  genetics
Hemoglobins, Abnormal
Heterozygote
Humans
Incidence
Infant, Newborn
Neonatal Screening* / methods,  utilization
Pilot Projects
Population Surveillance
Prenatal Diagnosis
Residence Characteristics / statistics & numerical data
Risk Factors
Sickle Cell Trait / diagnosis,  epidemiology,  genetics
Thalassemia / diagnosis,  epidemiology,  genetics
United Arab Emirates / epidemiology
Chemical
Reg. No./Substance:
0/Hemoglobins, Abnormal; 39346-78-6/hemoglobin D; 9034-61-1/Hemoglobin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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