Document Detail

Incidence and growth pattern of vestibular schwannomas in a Danish county, 1977-98.
MedLine Citation:
PMID:  10908969     Owner:  NLM     Status:  MEDLINE    
During a period of 21 years 162 acoustic neuromas or vestibular schwannomas (VS) were diagnosed in the county of Aarhus. During this period the incidence increased gradually, probably due to improvement of the quality of computed tomography imaging (CTI), and more widely available access to magnetic resonance imaging (MRI). Sixty-four patients were followed up by repeated CTI or MRI, whereas the remaining patients were referred for immediate operation. Six of the observed patients had their tumours removed after demonstration of continuous tumour growth. The observation of 64 tumours over periods between 5 months and 15 years provided useful information on the natural history of sporadic VS. Our results showed that 14 VS (22%) regressed, 35 VS (55%) did not grow or had only minimal growth (growth rate up to 1 mm/year), whereas 15 VS (23%) grew > 1 mm/year. All VS with positive growth had regular growth patterns.
F Mirz; C B Pedersen; B Fiirgaard; E Lundorf
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica. Supplementum     Volume:  543     ISSN:  0365-5237     ISO Abbreviation:  Acta Otolaryngol Suppl     Publication Date:  2000  
Date Detail:
Created Date:  2000-12-14     Completed Date:  2000-12-14     Revised Date:  2008-02-13    
Medline Journal Info:
Nlm Unique ID:  0370355     Medline TA:  Acta Otolaryngol Suppl     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  30-3     Citation Subset:  IM    
Department of Otorhinolaryngology, Aarhus University Hospitals, Denmark.
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MeSH Terms
Catchment Area (Health)
Denmark / epidemiology
Disease Progression
Magnetic Resonance Imaging
Middle Aged
Neuroma, Acoustic / diagnosis,  epidemiology*
Predictive Value of Tests
Prospective Studies
Time Factors
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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