| Incidence and diagnosis of unilateral arterial cerebral infarction in newborn infants. | |
| | |
MedLine Citation:
|
PMID: 15843270 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIMS: Magnetic resonance imaging (MRI) is accepted as the gold standard for the diagnosis of arterial cerebral infarction (ACI), but few studies have reported the incidence of neonatal ACI based on MRI findings. We provide new population-based epidemiologic and diagnostic data on all infants diagnosed between 1997 and 2002 in our center with an MRI-confirmed diagnosis of unilateral neonatal ACI. RESULTS: Nine patients were identified, giving an incidence of 1:2300 unilateral ACIs in our inborn population. In all patients the middle cerebral artery was affected. Seven patients showed epileptic seizures, usually starting within the first 3 days of life. EEG was pathologic in all patients. Only three infarctions were diagnosed by ultrasound. Initial MRI established diagnosis of ACI in eight out of nine patients and subsequent MRI described the exact location of infarctions in all patients. Six out of nine patients developed hemiparesis and five had deficits in language development. There is a substantial need for special care facilities and long-term therapeutic interventions. CONCLUSIONS: The incidence of neonatal ACI is higher than previously reported. The sensitivity of early cerebral ultrasound for diagnosis of ACI is low. Seizures in the first 3 days of life combined with pathologic EEG findings should lead to MRI, regardless of normal cerebral ultrasound. |
| | |
Authors:
|
Sven Schulzke; Peter Weber; Juerg Luetschg; Hubert Fahnenstich |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Journal of perinatal medicine Volume: 33 ISSN: 0300-5577 ISO Abbreviation: J Perinat Med Publication Date: 2005 |
Date Detail:
|
Created Date: 2005-04-21 Completed Date: 2005-07-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0361031 Medline TA: J Perinat Med Country: Germany |
Other Details:
|
Languages: eng Pagination: 170-5 Citation Subset: IM |
Affiliation:
|
Department of Neonatology, University Children's Hospital, Basel, Switzerland. sven.schulzke@unibas.ch |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cerebral Infarction
/
complications,
diagnosis*,
epidemiology*,
ultrasonography Electroencephalography Female Humans Infant, Newborn Language Development Disorders / etiology Magnetic Resonance Imaging Male Paresis / etiology Prognosis Retrospective Studies Seizures / etiology Switzerland / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Sudden infant death syndrome "gray zone" disclosed only by a study of the brain stem on serial secti...
Next Document: Non-hydropic intrauterine fetal death more than 5 months after primary parvovirus B19 infection.