Document Detail

Incidence and diagnosis of rotavirus infection in neonates: results of two studies.
MedLine Citation:
PMID:  1963446     Owner:  NLM     Status:  MEDLINE    
The present study investigates the incidence of human rotavirus excretion in neonates of two hospitals. From April 1, 1983 to March 31, 1984, rotaviruses were detected with Rotazyme in the feces of 57 (15%) of 383 neonates at the Department of Pediatrics, University of Berne, in a total in 71 (5.2%) of the 1369 stool samples tested. Of the 57 neonates with Rotazyme-positive stool samples, 53 (93%) were asymptomatic. The problems of the specificity of Rotazyme in neonatal feces and the possibility of rapid testing on neonatology wards are discussed. In a prospective study carried out in April 1986 at the "Schweizerische Pflegerinnenschule in Zurich", rotaviruses were detected with genome gel electrophoresis in the feces of 15 (63%) of 24 risk neonates in the premature baby ward and in 36 (46%) of 79 neonates from the infant nursery, in a total in 63 (34%) of the 188 stool samples tested. In this rotavirus outbreak all rotaviruses detected showed the same band pattern, and therefore had an identical electrophorotype. Symptoms and hospital hygiene aspects of this outbreak will be dealt with in subsequent papers.
R Zbinden; J Kunz; U B Schaad; U Schilt; R Slongo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  18     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  1990  
Date Detail:
Created Date:  1991-04-10     Completed Date:  1991-04-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  363-8     Citation Subset:  IM    
Institute of Immunology and Virology, University of Zurich, Switzerland.
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MeSH Terms
Diarrhea / microbiology
Electrophoresis, Agar Gel
Enzyme-Linked Immunosorbent Assay
Feces / microbiology
Infant, Newborn
RNA, Viral / analysis
Rotavirus / analysis,  genetics
Rotavirus Infections / diagnosis,  epidemiology*,  microbiology
Viral Envelope Proteins / analysis
Reg. No./Substance:
0/RNA, Viral; 0/Viral Envelope Proteins

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