Document Detail

Incidence of coronary artery disease in patients with valvular heart disease.
MedLine Citation:
PMID:  7459146     Owner:  NLM     Status:  MEDLINE    
The case notes, cardiac catheterisation data, and coronary arteriograms of 239 patients investigated for valvular heart disease during a five year period were reviewed. Angina present in 13 of 95 patients with isolated mitral valve disease, 43 of 90 patients with isolated aortic valve disease, and 18 of 54 patients with combined mitral and aortic valve disease. Significant coronary artery disease was present in 85 per cent of patients with mitral valve disease and angina, but in only 33 per cent of patients with aortic valve disease and angina. Patients with no chest pain still had a high incidence of coronary artery disease, significant coronary obstruction being present in 22 per cent with mitral valve disease, 22 per cent with aortic valve disease, and 11 per cent with combine mitral and aortic valve disease. Several possible clinical markers of coronary artery disease were examined but none was found to be of practical help. There was, however, a significant inverse relation between severity of coronary artery disease and severity of valve disease in patients with aortic valve disease. Asymptomatic coronary artery disease is not uncommon in patients with valvular heart disease and if it is policy to perform coronary artery bypass grafting in such patients, routine coronary arteriography must be part of the preoperative investigation.
G W Morrison; R D Thomas; S F Grimmer; P N Silverton; D R Smith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  44     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1980 Dec 
Date Detail:
Created Date:  1981-04-13     Completed Date:  1981-04-13     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  630-7     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Angina Pectoris / complications
Coronary Disease / complications*
Heart / physiopathology
Heart Valve Diseases / complications*,  physiopathology,  surgery
Middle Aged
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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