Document Detail

Incidence of congenital toxoplasmosis in live Guatemalan newborns.
MedLine Citation:
PMID:  1397218     Owner:  NLM     Status:  MEDLINE    
Five hundred and fifty samples of blood collected from the umbilical cords of an equivalent number of newborns were analyzed for serological evidence of congenital toxoplasmosis based on the detection of IgG and IgM. Six newborns presented serological evidence of congenital toxoplasmosis (IgM > 1:5, < 80 IU/ml), which represents an incidence of 10.9 per 1000 live births. During pregnancy four of the mothers of these six newborns were asymptomatic, whereas the other two mothers presented non-specific signs and symptoms. The six newborns did not present positive signs of acute toxoplasmosis at birth. Three false positive were identified, all secondary to the presence of a rheumatoid (RF) and/or antinuclear factor (ANF). And in one of them the diagnosis of congenital syphilis was confirmed. The percentage of women that tested serum positive for IgG antibodies increased with age, with 55.8% of the pregnant women testing serum-negative, therefore carrying the risk of acquired toxoplasmosis in future pregnancies.
J Sinibaldi; I De Ramirez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of epidemiology     Volume:  8     ISSN:  0393-2990     ISO Abbreviation:  Eur. J. Epidemiol.     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-11-23     Completed Date:  1992-11-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8508062     Medline TA:  Eur J Epidemiol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  516-20     Citation Subset:  IM    
Center for Studies of Sensory Impairment, Aging and Metabolism, Guatemala.
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MeSH Terms
Antibodies, Protozoan / analysis
Cross-Sectional Studies
Guatemala / epidemiology
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Infant, Newborn
Maternal Age
Toxoplasma / immunology
Toxoplasmosis, Congenital / epidemiology*,  immunology
Urban Population / statistics & numerical data*
Reg. No./Substance:
0/Antibodies, Protozoan; 0/Immunoglobulin G; 0/Immunoglobulin M

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