| Incidence of congenital toxoplasmosis in live Guatemalan newborns. | |
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MedLine Citation:
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PMID: 1397218 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Five hundred and fifty samples of blood collected from the umbilical cords of an equivalent number of newborns were analyzed for serological evidence of congenital toxoplasmosis based on the detection of IgG and IgM. Six newborns presented serological evidence of congenital toxoplasmosis (IgM > 1:5, < 80 IU/ml), which represents an incidence of 10.9 per 1000 live births. During pregnancy four of the mothers of these six newborns were asymptomatic, whereas the other two mothers presented non-specific signs and symptoms. The six newborns did not present positive signs of acute toxoplasmosis at birth. Three false positive were identified, all secondary to the presence of a rheumatoid (RF) and/or antinuclear factor (ANF). And in one of them the diagnosis of congenital syphilis was confirmed. The percentage of women that tested serum positive for IgG antibodies increased with age, with 55.8% of the pregnant women testing serum-negative, therefore carrying the risk of acquired toxoplasmosis in future pregnancies. |
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Authors:
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J Sinibaldi; I De Ramirez |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of epidemiology Volume: 8 ISSN: 0393-2990 ISO Abbreviation: Eur. J. Epidemiol. Publication Date: 1992 Jul |
Date Detail:
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Created Date: 1992-11-23 Completed Date: 1992-11-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8508062 Medline TA: Eur J Epidemiol Country: ITALY |
Other Details:
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Languages: eng Pagination: 516-20 Citation Subset: IM |
Affiliation:
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Center for Studies of Sensory Impairment, Aging and Metabolism, Guatemala. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Animals Antibodies, Protozoan / analysis Cross-Sectional Studies Female Guatemala / epidemiology Humans Immunoglobulin G / analysis Immunoglobulin M / analysis Incidence Infant, Newborn Maternal Age Pregnancy Toxoplasma / immunology Toxoplasmosis, Congenital / epidemiology*, immunology Urban Population / statistics & numerical data* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Protozoan; 0/Immunoglobulin G; 0/Immunoglobulin M |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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