Document Detail

Incidence and complexity of ventricular ectopy during Holter monitoring in patients with exercise-induced myocardial ischemia and normal or mildly reduced left ventricular function.
MedLine Citation:
PMID:  7566535     Owner:  NLM     Status:  MEDLINE    
We aimed to assess the relationship between frequent and complex ventricular ectopy by continuous electrocardigraphic 24-hours Holter monitoring in patients with coronary artery disease and inducible ischemia during exercise procedures. We investigated 609 consecutive patients. They were referred for chest pain (28% with a previous myocardial infarction, older than 6 months). In all population patients radionuclide ventriculography showed a global normal or mildly reduced left ventricular function (ejection fraction > 45%). All patients showed exercise-induced myocardial ischemia (ST depression) and exercise thallium-201 reversible defects. During Holter monitoring, in study population, divided according to incidence of premature ventricular complexes (PVC), we found a higher prevalence of complex ventricular arrhythmias (CVA) (bigeminy, couplets, ventricular tachycardia, multiformity) in patients with high incidence of PVC. The relationship between frequent and complex ventricular ectopy has been observed also during ischemic ST shifts occuring during 24-hours monitoring. In contrast, the R on T phenomenon was not related to incidence of PVC. Therefore, in patients with exercise-induced myocardial ischemia and global normal or mildly reduced left ventricular function there is a relationship between frequent and complex ventricular ectopy, as previously suggested in CAD patients with depressed left ventricular function.
M Romano; P Scarpato; S Cardei; I Monteforte; A Campopiano; L M Lembo; F De Falco; A Mazza; N Paglia; M Condorelli
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Minerva cardioangiologica     Volume:  43     ISSN:  0026-4725     ISO Abbreviation:  Minerva Cardioangiol     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1995-11-21     Completed Date:  1995-11-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0400725     Medline TA:  Minerva Cardioangiol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  237-40     Citation Subset:  IM    
I Clinica Medica, Università degli Studi Federico II, Napoli.
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MeSH Terms
Coronary Disease / physiopathology*
Electrocardiography, Ambulatory*
Exercise Test / adverse effects
Middle Aged
Myocardial Ischemia / etiology*
Ventricular Dysfunction, Left / physiopathology
Ventricular Premature Complexes / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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