Document Detail


Incidence of clindamycin resistance in clinical isolates of Staphylococcus aureus.
MedLine Citation:
PMID:  21537077     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Clindamycin is used in Staphylococcal infections and resistance patterns to Clindamycin vary between institutions. Inducible Clindamycin resistance is detected by the CLSI recommended D-test. This study was done to estimate the incidence of constitutive and inducible Clindamycin resistance in our hospital. Three hundred and seventy nine S.aureus isolates from clinical specimens collected over 6 months were tested for Clindamycin resistance using the D-test. Fourteen percent were Clindamycin resistant and among them 43% showed the inducible phenotype. Clindamycin resistance was higher among MRSA isolates (p < 0.001). It was concluded that Clindamycin should not be used empirically in serious Staphylococcal infections and that such studies are necessary to guide empiric therapy.
Authors:
Debmita Debdas; Sangeeta Joshi
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Publication Detail:
Type:  Journal Article     Date:  2011-04-26
Journal Detail:
Title:  Journal of infection in developing countries     Volume:  5     ISSN:  1972-2680     ISO Abbreviation:  J Infect Dev Ctries     Publication Date:  2011  
Date Detail:
Created Date:  2011-05-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101305410     Medline TA:  J Infect Dev Ctries     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  316-7     Citation Subset:  IM    
Affiliation:
Jyoti Laboratory, Assam Trunk Road, Jorhat - 785001, Assam, India. debdas.debmita@rediffmail.com.
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